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Table 1 Details of the eight enrolled studies

From: Can high-flow nasal cannula reduce the rate of reintubation in adult patients after extubation? A meta-analysis

Author(Year) Study design NCT No. Country Control Population Underlying disease Outcomea
Corley 2015 Randomised controlled trial ACTRN12610000942055 Australia Standard oxygen therapy 155 Cardiac surgery
Fernández 2017 Randomised controlled trial NCT01820507 Spain COT 155 Chronic obstructive pulmonary disease, heart failure
Futier 2016 Multicenter randomized trial NCT01887015 France Standard oxygen therapy 220 Major abdominal surgery
Hernández 2016 Multicenter randomized trial NCT01191489 Spain COT 527 Medical,trauma,surgical
Hernández 2016 (2) Multicenter randomized trial NCT01191489 Spain NIPPV 604 Medical,trauma,surgical
Maggiore 2014 Randomized controlled open-label trial NCT01575353 Italian Venturi mask 105 Pneumonia, multiple trauma, atelectasis, shock, cardiogenic pulmonary edema, cardiac arrest, other
Parke 2013 Pragmatic randomized controlled trial ACTRN12610000973011 New Zealand Simple facemask or nasal prongs 340 Cardiac surgery
Stéphan 2016 Multicente,r randomised,noinferiorty trail NCT01458444 France NIPPV 830 Cardiothoracic surgery
  1. aOutcome measures include:mortality;rate of endotracheal intubation; length of ICU stay;adverse events;respiratory variables;patient comfort;dyspnea scale
  2. AECOPD acute exacerbation of chronic obstructive pulmonary disease; ARDS acute respiratory distress syndrom; ARF acute respiratory failure; COPD chronic obstructive pulmonary disease;COT conventional oxygen therapy; HFNC high flow nasal cannula; NIPPV noninvasive positive pressure ventilation; NR not report; SIRS systemic inflammatory response syndrome