Variablesa | No Lavage (n = 40) | Lavage (n = 38) | P value |
---|---|---|---|
Age (median years [IQR]) | 46 (39–54) | 49 (44–61) | 0.089 |
Male | 24 (60.0) | 23 (60.5) | 0.962 |
Smoking status (n = 73) |  |  | 0.878 |
 Never smoker | 19 (50.0) | 15 (42.9) |  |
 Ex-smoker | 9 (23.7) | 9 (25.7) |  |
 Current smoker | 10 (26.3) | 11 (31.4) |  |
Presence of symptoms | 24 (60.0) | 38 (100.0) | <0.001 |
 Presence of dyspnea | 16 (40.0) | 34 (89.5) | <0.001 |
Presence of dust exposure (n = 71) | 19 (48.7) | 15 (46.9) | 0.403 |
Type of exposed dust | |||
 Farming | 0 (0) | 5 (33.3) | 0.011 |
 Metal | 6 (31.6) | 3 (20.0) | 0.697 |
 Stone or sand | 6 (31.6) | 1 (6.7) | 0.104 |
 Chemical or paint | 4 (21.0) | 2 (13.3) | 0.672 |
 Diesel | 3 (15.8) | 2 (13.3) | 1.000 |
 Textile | 0 (0) | 1 (6.7) | 0.441 |
 Wood | 0 (0) | 1 (6.7) | 0.441 |
Disease severity scoreb (n = 65) |  |  | 0.001 |
 1 | 9 (31.0) | 0 (0) |  |
 2 | 13 (44.8) | 20 (55.6) |  |
 3 | 7 (24.1) | 9 (25.0) |  |
 4 | 0 (0) | 4 (11.1) |  |
 5 | 0 (0) | 3 (8.3) |  |
FVC % predicted | 86.7 ± 15.8 | 75.5 ± 15.7 | 0.005 |
DLCO % predicted | 82.3 ± 20.7 | 57.5 ± 23.3 | <0.001 |
PaO2 mm Hg | 88.2 ± 30.8 | 71.7 ± 15.4 | 0.006 |
D(A-a)O2 mm Hg | 23.6 ± 14.5 | 31.6 ± 15.1 | 0.036 |
LDH U/L | 389.4 ± 171.9 | 450.6 ± 188.6 | 0.239 |
CEA ng/mL | 4.2 ± 1.9 | 10.3 ± 10.8 | 0.760 |