Fig. 4
Estimate of annual loss in FEV1 having a serum biomarker concentration at the level of the 25th percentile (dashed line) and 75th percentile (full line). C1M: 25 percentile 46.3 ng/mL; 75 percentile: 105.5 ng/mL; C6M: 25 percentile 11.7 ng/mL; 75 percentile: 22.5 ng/mL, hsCRP: 25 percentile 1.50 ng/mL; 75 percentile: 7.45 ng/mL. Subject characteristics: Male, 63 years of age, BMI 26.9 kg/m2, former smoker with a history of 43 pack-years of smoking, 1 exacerbation in the previous 12 months, no exacerbations during follow-up, bronchodilator irreversible, and absence of emphysema and chronic bronchitis