The impacts of baseline ventilator parameters on hospital mortality in acute respiratory distress syndrome treated with venovenous extracorporeal membrane oxygenation: a retrospective cohort study

Table 1 Patient characteristics before venovenous extracorporeal membrane oxygenation

	All (n = 106)	Survivor (n = 50)	Non-survivor (n = 56)	P
Age (year)	53 ± 15	51 ± 15	55 ± 15	0.11
Male	71 (67)	35 (70)	36 (64)	0.53
Predicted body weight^a (kg)	55 ± 14	55 ± 16	55 ± 11	0.89
Hospital day before ECMO	6 (1–14)	2(1–9)	11(4–20)	<0.001*
Mechanical ventilation before ECMO (day)	3 (1–9)	1(0–4)	6(1–12)	<0.001*
Cause of ARDS
Viral pneumonia	24 (21)	11 (22)	13 (23)	0.88
Bacterial pneumonia	38 (37)	16 (32)	22 (39)	0.54
Fungal pneumonia	3 (3)	0	3 (6)	0.25
Aspiration pneumonitis	3 (3)	3 (6)	0	0.10
Other acute respiratory diagnoses	38 (36)	20 (40)	18 (32)	0.40
Acute associated infection	24 (21)	11 (22)	13 (23)	0.88
Immunocompromised status^b	37 (35)	11 (22)	26 (46)	0.008*
Renal failure requiring dialysis	28 (26)	13 (26)	15 (27)	0.93
Creatinine (mg/dL)	1.6 (0.8–3.4)	2.8 ± 3.3	2.3 ± 2.3	0.36
Total bilirubin (mg/dL)	1.5 ± 2.5	1.1 ± b1.2	1.9 ± 3.2	0.14
Platelet count (10⁹/L)	137 (83–218)	172 (113–237)	106 (60–161)	0.002*
Hemoglobin (g)	10 (9–12)	11 (9–12)	10 (9–11)	0.08
SOFA score	10 (8–11)	9 (7–10)	10 (9–12)	0.002*
RESP score	2 ± 3	2 ± 3	1 ± 3	0.05*

Data were presented as mean ± standard deviation in normal-distributed numerical variables, median (interquartile range) in numerical variables not normal-distributed, and n (%) in categorical variables. ECMO Extracorporeal membrane oxygenation, SOFA sequential organ failure assessment, RESP score Respiratory extracorporeal membrane oxygenation survival prediction score, ARDS Acute respiratory distress syndrome. ^a Ideal body weight is calculated by the ARDSnet formulas. ^bImmunocompromised status includes hematologic malignancy, solid tumor, solid organ transplantation, liver cirrhosis Child B or C, or autoimmune diseases requiring long-term immunosuppressive therapy
*p < 0.05. (in the comparisons between survivors and non-survivors)

ISSN: 1471-2466