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Table 1 Patients characteristics (n = 84)

From: The association of N-terminal pro-brain-type natriuretic peptide with hemodynamics and functional capacity in therapy-naive precapillary pulmonary hypertension: results from a cohort study

Clinical profile

 

 Female / male [n (%)]

46 (54.8) / 38 (45.2)

 Age (years)

70.6 ± 1.41

 BMI (kg/m2)

27.1 ± 0.60

 PHgroup 1 / 3 / 4 / 5 [n (%)]

63 (75) / 7 (8.3) / 12 (14.3) / 2 (2.4)

NT-proBNP

 

 NT-proBNP level (pg/ml)

1500 (38–13,538)

 NT-proBNP ratio

7.53 (0.09–60.60)

6-min walking test

 

 Distance (m)

305 ± 14.3

 % of norm

62.3 ± 2.72

 Breaks (n)

0 (0–6)

 Borg scale points (1–10)

4.10 ± 0.29

Right heart catheterization

 

 Mean PAP (mmHg)

41.0 ± 1.22

 Cardiac output (l/min)

4.39 ± 0.14

 Cardiac index (l/min/m2)

2.43 ± 0.10

 PVR (Wood units)

7.40 (3.00–18.2)

 Mean RAP (mmHg)

6.0 (1–20)

 SvO2 (%)

61.4 ± 0.93

Lung function

 

 DLCO (%)

52.9 ± 2.59

 PaO2 at rest (mmHg)

56.8 ± 1.57

 PaO2 at peak exercise (mmHg)

57.4 ± 1.84

Cardiopulmonary exercise testing

 

 Work capacity (watts)

47.0 (25–150)

 VO2 (ml/min)

953 ± 37.5

 VO2/kg

13.0 ± 0.45

 AT (ml/min/kg)

9.64 ± 0.40

 O2 pulse at peak exercise (ml/min/beat)

8.30 (3.50–16.0)

 Ve (L/min)

52.1 ± 2.11

 Ve/VO2

40.5 ± 1.37

 Ve/VCO2

47.2 ± 1.58

 AaDO2 (mmHg)

49.0 ± 1.76

 Vd/Vt (%)

37.1 ± 1.50

 Ve/VCO2 slope

44.2 ± 2.06

  1. If not stated otherwise, data is presented as mean ± SEM or as median (range)
  2. BMI: body mass index, NT-proBNP ratio: NT-proBNP level divided by the age-adjusted normal upper range, PAP: pulmonary arterial pressure, PVR: pulmonary vascular resistance, RAP: right atrial pressure, SvO 2: mixed venous oxygen saturation, DLCO: lung diffusing capacity for carbon monoxide, PaO 2: arterial oxygen pressure, VO 2: peak oxygen uptake, AT: anaerobic threshold, Ve: peak minute ventilation, Ve/VO 2: oxygen equivalent at anaerobic threshold, Ve/VCO 2: carbon dioxide equivalent at anaerobic threshold, AaDO 2: alveolar-arterial oxygen difference at peak exercise, Vd/Vt: functional dead space ventilation at peak exercise, Ve/VCO 2 slope: slope of minute ventilation to carbon dioxide output