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Table 2 Characteristics, laboratory values, and outcomes of cases (patients with ARDS) and matched controls (patients without ARDS) included in the propensity score matched analysis

From: Plasma surfactant protein-D as a diagnostic biomarker for acute respiratory distress syndrome: validation in US and Korean cohorts

  Cases
(patients with ARDS)
Controls
(patients without ARDS)
P-value
Number 38 38  
Age 57.0 (45.0–67.0) 62.0 (50.0–72.0) 0.53
Female 13 (34.2) 13 (34.2) 1.00
Study site    0.16
Korea 18 (46.2) 10 (25.6)  
New York 7 (17.9) 10 (25.6)  
Boston 14 (35.9) 19 (48.7)  
APACHE IIa 27.5 (24.0–33.0) 26.0 (18.0–35.0) 0.62
Sepsisb 16 (42.1) 33 (86.8) <0.001
Septic shock 7 (18.4) 4 (10.5) 0.33
Pneumonia 33 (86.8) 33 (86.8) 1.00
Intubation 34 (89.5) 32 (84.2) 0.55
Procalcitonin, ng/mLc 6.0 (2.1–36.4) 0.8 (0.2–4.8) 0.03
Creatinine, mg/dLa 0.8 (0.6–1.6) 1.0(0.7–1.9) 0.48
Bilirubin, mg/dLa 1.0 (0.6–3.0) 3.1 (0.5–6.1) 0.61
pH in arterial blooda 7.34 (7.28–7.45) 7.40 (7.28–7.46) 0.79
PaO2, mmHga 72.9 (62.8–98.3) 87.7 (69.3–113.3) 0.92
PaCO2, mmHga 36.9 (29.8–44.9) 32.4 (26.0–40.9) 0.82
Lactate, mEq/L 2.4 (1.5–3.5) 2.0 (1.3–3.4) 0.23
Albumin, g/dL 2.5 (2.1–3.0) 2.9 (2.4–3.5) 0.2
SP-D, ng/mL 20.8 (12.7–38.4) 7.9 (4.1–17.0) 0.001
Length of ICU stay 8.0 (5.0–15.0) 4.0 (2.0–10.0) 0.006
ICU Mortality 7 (18.4) 6 (15.8) 0.76
In-hospital Mortality 14 (35.9) 10 (26.3) 0.32
  1. Abbreviations: ARDS acute respiratory distress syndrome, APACHE Acute Physiology and Chronic Health Evaluation, PaO 2 arterial oxygen tension, PaCO 2 arterial carbon dioxide tension, SP-D Surfactant protein D, ICU intensive care unit
  2. Data are presented as median (interquartile range) or as number (%)
  3. aAt admission to medical ICU
  4. bIt does not include patients with septic shock
  5. cData are available for 19 patients (12 patients with and 7 patients without ARDS)