A simple prediction tool for inhaled corticosteroid response in asthmatic children

BMC Pulmonary Medicine

Table 4 Performance measures of the prediction tool at different cutoff values

Score cutoff	Sensitivity	Specificity	PPV ^b	NPV ^b	LR+	LR-
≧1	0.96	0.13	0.37	0.86	1.10	0.31
≧2	0.96	0.18	0.38	0.89	1.16	0.23
≧3	0.75	0.69	0.56	0.84	2.41	0.36
≧4	0.63	0.78	0.60	0.80	2.81	0.48
5	0.21	1.00	1.00	0.70	^a	0.79

LR + positive likelihood ratio, LR - negative likelihood ratio, NPV negative predictive value, PPV positive predictive value
^aGreat uncertainty of estimate because of sensitivity and specificity close to 0 or 1
^bPositive and negative predictive value will change depending on the prevalence on non-responders in different populations

ISSN: 1471-2466