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Fig. 2 | BMC Pulmonary Medicine

Fig. 2

From: Napsin A levels in epithelial lining fluid as a diagnostic biomarker of primary lung adenocarcinoma

Fig. 2

Computed tomography (CT) and immunohistological findings in a representative case. a A lung CT image shows a 20-mm, partly solid, ground-glass opacity nodule (arrowhead) in the right upper lobe. b Minimally invasive adenocarcinoma. The cancer demonstrates predominant lepidic growth with <5-mm invasion. The cancer cells have polygonal cytoplasm and atypical nuclei (inset) (hematoxylin-eosin staining, original magnification ×40 and high magnification ×100). c Immunohistological staining for napsin A. Napsin A is strongly positive in adenocarcinoma cells (inset for greater detail) (original magnification ×40 and high magnification ×100). d Immunohistological staining for CEA. CEA is strongly positive in adenocarcinoma cells (inset for greater detail) (original magnification ×40 and high magnification ×100). CT: computed tomography; CEA: carcinoembryonic antigen

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