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Table 4 Odds Ratios (95% Confidence Intervals) for Chronic Obstructive Pulmonary Disease among Adults Aged 45-74 Years in the Southern Cone of Latin America

From: Estimating prevalence of chronic obstructive pulmonary disease in the Southern Cone of Latin America: how different spirometric criteria may affect disease burden and health policies

Risk factors

 

COPD according FEV1/FVC

Odds ratios and 95% CI

COPD according LLN

Odds ratios and 95% CI

Model 1

Model 2

Model 1

Model 2

Sex, men

 

1.7 (1.4, 2.1)

1.8 (1.4, 2.3)

1.5 (1.1, 2.0)

1.5 (1.1, 2.2)

Age, years

45-54

ref

ref

ref

ref

55-64

2.1 (1.5, 2.9)

2.3 (1.7, 3.3)

1.4 (1.0, 2.0)

1.5 (1.0, 2.2)

65-74

4.6 (3.4, 6.2)

6.1 (4.4, 8.6)

2.1 (1.4, 3.0)

2.7 (1.7, 4.1)

< High-school education

 

1.4 (1.1, 1.8)

1.5 (1.1, 2.0)

1.7 (1.2, 2.5)

1.8 (1.1, 2.7)

Body-mass index <25 kg/m2

 

1.7 (1.3, 2.1)

1.4 (1.1, 1.9)

2.2 (1.6, 3.0)

1.9 (1.3, 2.7)

Cigarette smoking

Never

ref

ref

ref

ref

Former

1.3 (0.9, 1.7)

1.1 (0.8, 1.4)

1.4 (1.0, 2.2)

1.2 (0.7, 1.8)

Current

2.8 (2.1, 3.7)

2.8 (2.1, 3.8)

3.1 (2.1, 4.6)

3.1 (2.1, 4.5)

Lifetime exposure in current smokers, pack-years

<10

ref

ref

10-19

2.1 (1.0, 4.4)

1.0 (0.4, 2.7)

≥20

4.0 (2.1, 7.7)

2.2 (1.1, 4.4)

Second-hand smoking

 

1.0 (0.6, 1.6)

0.8 (0.4, 1.4)

Exposure to biomass

 

1.2 (0.9, 1.6)

1.2 (0.8, 1.7)

1.3 (0.8, 2.1)

1.2 (0.7, 2.0)

Self-reported history of asthma

 

8.8 (6.2, 12.5)

9.8 (6.7, 14.4)

10.8 (7.3, 16.0)

13.0 (8.4, 19.9)

Self-reported history of tuberculosis

 

3.9 (1.8, 8.3)

3.3 (1.4, 7.8)

6.4 (2.9, 14.2)

5.6 (2.2, 14.3)

  1. Model 1: model for each risk factor adjusted for age, sex, and study site; Model 2: model adjusted for age, sex, study site, high school education, body-mass index, cigarette smoking, exposure to biomass, self-reported history of asthma, and self-reported history of tuberculosis