Overexpression of EMMPRIN is associated with lymph node metastasis and advanced stage of non-small cell lung cancer: a retrospective study

Table 3 Correlation between clinico-pathological parameters and the expressions of EMMPRIN in serum of NSCLC (n=72)

Parameter	Group	N	Expressions of EMMPRIN in serum of NSCLC
Parameter	Group	N	Value (pg/ml)	Degree of freedom	Statistical value	P value
Resource
	Normal	60	59.04±10.97	130	18.411	<0.001
	NSCLC	72	101.93±15.01	130	18.411	<0.001
Gender
	Male	46	100.86±15.09	70	-0.800	0.43
	Female	26	103.81±14.98	70	-0.800	0.43
Ages
	<60	31	101.12±12.06	70	-0.396	0.69
	≥60	41	102.56±17.03	70	-0.396	0.69
Smoking
	Yes	28	103.23±16.06	70	0.585	0.56
	No	44	101.09±14.13	70	0.585	0.56
Histology
	LAC	33	104.02±13.13	70	1.087	0.28
	LSCC	39	100.16±16.39	70	1.087	0.28
Pathological grade
	Poorly	24	105.33±11.46^★	2	3.719	0.029
	Moderately	19	106.24±14.92^★
	Well	29	96.28±16.27
Lymphatic invasion
	N0 - N1	26	91.78±9.97	70	-4.983	<0.001
	N2 - N3	46	107.66±14.39	70	-4.983	<0.001
pTNM
	IIA - IIIA	35	93.92±10.45	70	-5.125	<0.001
	IIIB - IV	37	109.49±14.83	70	-5.125	<0.001

M±SD, mean±standard deviation; LAC, lung adenocarcinoma; LSCC, lung squamous cell carcinoma; ^★, poor and moderate differentiation compared with well differentiation; N, lymphatic metastasis; pTNM, clinical stage of lung cancer

ISSN: 1471-2466