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Table 4 Criterion values and coordinates of the ROC curve for EMMPRIN

From: Overexpression of EMMPRIN is associated with lymph node metastasis and advanced stage of non-small cell lung cancer: a retrospective study

Criterion

Sensitivity

95% CI

Specificity

95% CI

+LR

95% CI

-LR

95% CI

>68.6

100.00

95.0 - 100.0

88.33

77.4 - 95.2

8.57

7.8 - 9.4

0.00

-

>70

97.22

90.3 - 99.7

88.33

77.4 - 95.2

8.33

7.5 - 9.2

0.031

0.007 - 0.1

>80.1

97.22

90.3 - 99.7

91.67

81.6 - 97.2

11.67

10.7 - 12.7

0.030

0.006 - 0.2

>80.3 *

97.22

90.3 - 99.7

95.00

86.1 - 99.0

19.44

18.1 - 20.9

0.029

0.005 - 0.2

>87.6

84.72

74.3 - 92.1

95.00

86.1 - 99.0

16.94

15.1 - 19.0

0.16

0.05 - 0.6

>91.4

76.39

64.9 - 85.6

96.67

88.5 - 99.6

22.92

20.0 - 26.3

0.24

0.06 - 1.0

>93.9

69.44

57.5 - 79.8

100.00

94.0 - 100.0

-

-

0.31

-

  1. 95% CI, 95% confidence; +LR, positive likelihood ratio; -LR, negative likelihood ratio; *cut-off value of EMMPRIN for distinguishing NSCLC patients from control group