Impact of chronic Pseudomonas aeruginosa infection on health-related quality of life in Mycobacterium avium complex lung disease

Table 2 Pulmonary function test results, high-resolution computed tomography findings and laboratory data in 244 Mycobacterium avium complex lung disease patients with and without chronic Pseudomonas aeruginosa infection

	All patients (n = 244)	With chronic infection (n = 19)	Without chronic infection (n = 225)	P value
PFT	(n = 243)	(n = 19)	(n = 224)
%FVC	95 (81–108)	94 (75–102)	96 (82–109)	0.234
%FEV₁	87 (73–99)	81 (66–98)	88 (74–100)	0.079
HRCT findings
Cavitary lesion	59 (24)	4 (21)	55 (24)	1.000
Presence of bronchiectasis	233 (95)	19 (100)	214 (95)	0.609
Modified Reiff score	4 (2–6)	5 (3–7)	3 (2–6)	0.028
Laboratory data
WBC/μL	5250 (4500–6375)	5700 (4700–7400)	5200 (4500–6200)	0.209
Haemoglobin, g/dL	13 (12–14)	12 (11–13)	13 (12–14)	0.049
CRP, mg/dL	0.1 (0.0–0.3)	0.3 (0.1–1.9)	0.1 (0.0–0.3)	0.005

Data show the median (interquartile range) or number (%) of patients
PFT, pulmonary function test; FVC, forced vital capacity; FEV ₁, forced expiratory volume in the first second; HRCT, high-resolution computed tomography; WBC, white blood cell; CRP, C-reactive protein

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