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Table 3 Pathways significantly associated with protein-protein interaction nodes

From: Gene expression analysis in asthma using a targeted multiplex array

Pathway name Hits/Total FDR
Up-Regulated Pathways
Degradation of Collagen 4/61 0.003
Extracellular Matrix Organization 5/157 0.003
Degradation of Extracellular Matrix 4/77 0.004
Assembly of Collagen Fibrills and Other Multimeric Structures 3/54 0.04
Collagen Biosynthesis and Modifying Enzymes 3/62 0.04
Down-regulated pathways
Integrin Cell Surface Interactions 6/85 0.0007
Signal Transduction 17/1690 0.004
Cell-Cell Communication 6/143 0.004
Platelet Activation, Signaling, and Aggregation 7/220 0.004
TGF-beta Receptor Signaling in EMT 3/17 0.009
Hemostatis 9/511 0.01
Signaling by TGF-beta Receptor Complex 4/70 0.02
Sema4D Induced Cell Migration and Growth-Cone Collapse 3/29 0.03
Sema4D in Semaphorin Signaling 3/34 0.04
Fc-gamma Receptor Dependent Phagocytosis 4/86 0.04