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Table 4 Pathways enriched in differentially co-expressed genes. p-value comes from using list of 334 genes as background

From: Gene expression analysis in asthma using a targeted multiplex array

Coexpressed in Non-asthmatics

Cluster #

# Genes in Cluster

# Genes From Cluster in Pathway

Biological Process

p-value

10

25

3

Regulation of Cell-Cell Adhesion Involved in Gastrulation

2.0 × 10−1

13

Regulation of Multicellular Organismal Development

2.0 × 10−1

8

Regulation of Cell Adhesion

2.0 × 10−1

53

6

4

Cell Migration

4.0 × 10−1

4

Locomotion

5.7 × 10−1

4

Localization of Cell

4.0 × 10−1

Coexpressed in Asthmatics

16

6

3

Cytoplasmic Pattern Recognition Receptor Signaling Pathway in Response to Virus

3.0 × 10 −4

3

Positive Regulation of Type 1 Interferon Production

3.9 × 10 −3

3

Negative Regulation of Type 1 Interferon Production

2.0 × 10 −3

20

6

4

Activation of MAPK Activity

6.9 × 10−2

4

Peptidyl-Tyrosine Phosphorylation

7.9 × 10−2

3

Eicosanoind Biosynthetic Pathway

7.9 × 10−2

11

9

3

Odontogenesis

4.2 × 10−1

17

7

4

Response to Bacterium

3.9 × 10−1

  1. Bolded pathways highlight those that reached statistical significance in the co-expression data set