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Table 4 Pathways enriched in differentially co-expressed genes. p-value comes from using list of 334 genes as background

From: Gene expression analysis in asthma using a targeted multiplex array

Coexpressed in Non-asthmatics
Cluster # # Genes in Cluster # Genes From Cluster in Pathway Biological Process p-value
10 25 3 Regulation of Cell-Cell Adhesion Involved in Gastrulation 2.0 × 10−1
13 Regulation of Multicellular Organismal Development 2.0 × 10−1
8 Regulation of Cell Adhesion 2.0 × 10−1
53 6 4 Cell Migration 4.0 × 10−1
4 Locomotion 5.7 × 10−1
4 Localization of Cell 4.0 × 10−1
Coexpressed in Asthmatics
16 6 3 Cytoplasmic Pattern Recognition Receptor Signaling Pathway in Response to Virus 3.0 × 10 −4
3 Positive Regulation of Type 1 Interferon Production 3.9 × 10 −3
3 Negative Regulation of Type 1 Interferon Production 2.0 × 10 −3
20 6 4 Activation of MAPK Activity 6.9 × 10−2
4 Peptidyl-Tyrosine Phosphorylation 7.9 × 10−2
3 Eicosanoind Biosynthetic Pathway 7.9 × 10−2
11 9 3 Odontogenesis 4.2 × 10−1
17 7 4 Response to Bacterium 3.9 × 10−1
  1. Bolded pathways highlight those that reached statistical significance in the co-expression data set