Table 4 The differences between baseline and one-year follow-up among the three subgroups (n = 203)
|  | Total | Subgroup 1 (n = 116) | Subgroup 2 (n = 33) | Subgroup 3 (n = 54) | p-value†| Adjusted p-value‡ |
|---|---|---|---|---|---|---|
Δ Pre FEV1 | −0.01 ± 0.26 | 0.01 ± 0.24 | −0.06 ± 0.32 | 0.02 ± 0.27 | 0.3360 | 0.1520 |
Δ Post FEV1 | −0.01 ± 0.23 | −0.002 ± 0.20 | −0.05 ± 0.27 | 0.01 ± 0.25 | 0.4254 | 0.2605 |
Δ mMRC | −0.005 ± 1.001 | −0.33 ± 0.98 | 0.42 ± 0.79 | 0.39 ± 0.96 | <.0001 | <.0001 |
Δ CAT total | 1.12 ± 8.10 | −0.75 ± 7.92 | 3.82 ± 7.99 | 2.89 ± 8.06 | 0.0021 | 0.0010 |
Exacerbation requiring | ||||||
 Steroid/antibiotic at outpatient clinic | 3(1.5) | 1(0.9) | 1(3.0) | 1(1.8) | 0.6376 | 0.4649 |
 Hospitalization | 16(7.9) | 3(2.6) | 5(15.2) | 8(14.8) | 0.0054 | 0.1127 |
Symptoms | ||||||
 Cough | 81(39.9) | 35(30.2) | 19(57.6) | 27(50.0) | 0.0037 | 0.0102 |
 Sputum | 76(37.4) | 34(29.3) | 20(60.6) | 22(40.7) | 0.0039 | 0.0028 |
 Chronic Bronchitis | 57(28.1) | 24(20.7) | 16(48.5) | 17(31.5) | 0.0059 | 0.0055 |