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Table 1 Selection criteria of the study population

From: Nerve ablation after bronchial thermoplasty and sustained improvement in severe asthma

Inclusion Criteria
 1. Patients with severe persistent asthma, stable for at least 3 weeks
 2. Patients receiving regular treatment with inhaled corticosteroids (beclomethasone ≥1000 mcg or equivalent) and long-acting ß agonists (LABA) (salmeterol ≥100 mcg or equivalent)
 3. Asthma Quality of Life Questionnaire (AQLQ) score < 6.25
 4. Asthma Control Questionnaire (ACQ) score > 2.0
 5. Post-bronchodilator Forced Expiratory Volume in 1 s (FEV1) ≥ 60% predicted
 6. Patients not smoking for at least one year
Exclusion Criteria
 1. Life threatening asthma exacerbation
 2. Concomitant respiratory diseases (e.g. COPD or emphysema)
 3. Use of ß-blocker drugs
 4. Severe active infection in the last 2 weeks
 5. Pacemaker, internal defibrillator or other implanted electronic device
 6. Known sensitivity to medications used to perform bronchoscopy, including lidocaine, atropine and benzodiazepines
 7. Current uncontrolled bleeding disorders
 8. Inability to stop taking, prior to the procedure, anticoagulants, antiplatelet agents, aspirin or non-steroidal anti-inflammatory drugs
 9. Age < 18 years
 10. Pregnancy