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Table 2 Timing of functional and clinical evaluations and endoscopic procedures

From: Nerve ablation after bronchial thermoplasty and sustained improvement in severe asthma

  enrolment BT 1° Baseline BT 2° 1 month after T0 BT3° 2 months after T0 Follow-up 3 months after T2 Follow-up 12 months after T2
   T0 T1 T2 T3 T12
Consent X      
Spirometry X     X X
ACQ X     X X
AQLQ X     X X
Drug Treatment   X X X   X
Safety   X X X X X
Exacerbations   X     X
Hospitalizations   X     X
BT   Treatment of right lower lobe Treatment of left lower lobe Treatment of right upper lobe Treatment of left upper lobe   
Biopsies   Biopsy of left lower lobe Biopsy of right lower lobe Biopsy of right lower lobe   Biopsy of right lower lobe
  1. Legend: T0 baseline, T1 one month after T0; T2 two months after T0, T3 three months after T2, T12 twelve months after T2 (i.e. 14 months after baseline)