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Table 4 Clinical Characteristics of patients

From: Nerve ablation after bronchial thermoplasty and sustained improvement in severe asthma

  T0 (N = 12) T3 (N = 11) T12 (N = 10) p value § p value (T0 vs T3) p value (T0 vs T12) p value (T3 vs T12)
OCS – mg/ (range) 21.2 ± 13.8 (0–50) 18.7 ± 10.8 (0–25) 6.6 ± 8.6 (0–25) 0.004   0.026 0.007
FEV1% (range) 77.4 ± 14.7 (56–100) 69.0 ± 15.2 (37–97) 76.2 ± 19.6 (53–98) 0.017    
FEV1 (L) (range) 2.3 ± 0.75 (1.0–3.7) 2.0 ± 0.71 (1.0–3.3) 2.3 ± 1.11 (0.7–4.7) 0.348    
FEV1/FVC (%) (range) 64.0 ± 10.7 (47–79) 60.5 ± 13.0 (33–79) 62.8 ± 12.3 (39–79) 0.627    
RV (L) (range) 2.3 ± 1.1 (1.0–4.2) 2.1 ± 0.73 (1–4) 2.0 ± 0.66 (1.1–3.4) 0.416    
TLC (L) (range) 5.9 ± 1.5 (3.9–9.1) 5.6 ± 1.4 (3.8–8.7) 5.3 ± 1.3 (4.1–8.4) 0.322    
AQLQ (range) 2.9 ± 0.9 (1.8–4.2) 4.8 ± 1.2 (1.9–6.1) 5.7 ± 0.7 (4.4–6.6) 0.000 0.031 0.000  
ACQ (range) 4.7 ± 0.8 (2.8–5.8) 1.8 ± 1.1 (0.2–3.8) 1.5 ± 0.9 (0–2.6) 0.000 0.000 0.000  
Exacerbations/patient/year (range) 4.7 ± 2.0 (3–10) 0.9 ± 0.9 (0–3) 0.6 ± 0.7 (0–2) 0.000 0.003 0.001  
Hospitalizations/patient/year (range) 1.2 ± 1.7 (0–6) 0 0.1 ± 0.3 (0–1) 0.049    
  1. Legend: Values are means ± SD. missing data in 3 patients. P values are based on § repeated measure ANOVA (comparison among time points) and post hoc tests with Bonferroni correction (comparison between time points). Only significant values (p < 0.05) are reported