Table 4 Clinical Characteristics of patients
From: Nerve ablation after bronchial thermoplasty and sustained improvement in severe asthma
T0 (N = 12) | T3 (N = 11) | T12 (N = 10) | p value § | p value (T0 vs T3) | p value (T0 vs T12) | p value (T3 vs T12) | |
|---|---|---|---|---|---|---|---|
OCS – mg/ (range) | 21.2 ± 13.8 (0–50) | 18.7 ± 10.8 (0–25) | 6.6 ± 8.6 (0–25) | 0.004 | 0.026 | 0.007 | |
FEV1% (range) | 77.4 ± 14.7 (56–100) | 69.0 ± 15.2 (37–97) | 76.2 ± 19.6 (53–98) | 0.017 | |||
FEV1 (L) (range) | 2.3 ± 0.75 (1.0–3.7) | 2.0 ± 0.71 (1.0–3.3) | 2.3 ± 1.11 (0.7–4.7) | 0.348 | |||
FEV1/FVC (%) (range) | 64.0 ± 10.7 (47–79) | 60.5 ± 13.0 (33–79) | 62.8 ± 12.3 (39–79) | 0.627 | |||
RV (L) (range) | 2.3 ± 1.1 (1.0–4.2) | 2.1 ± 0.73 (1–4) | 2.0 ± 0.66 (1.1–3.4) | 0.416 | |||
TLC (L) (range) | 5.9 ± 1.5 (3.9–9.1) | 5.6 ± 1.4 (3.8–8.7) | 5.3 ± 1.3 (4.1–8.4) | 0.322 | |||
AQLQ (range) | 2.9 ± 0.9 (1.8–4.2) | 4.8 ± 1.2 (1.9–6.1) | 5.7 ± 0.7 (4.4–6.6) | 0.000 | 0.031 | 0.000 | |
ACQ (range) | 4.7 ± 0.8 (2.8–5.8) | 1.8 ± 1.1 (0.2–3.8) | 1.5 ± 0.9 (0–2.6) | 0.000 | 0.000 | 0.000 | |
Exacerbations/patient/year (range) | 4.7 ± 2.0 (3–10) | 0.9 ± 0.9 (0–3) | 0.6 ± 0.7 (0–2) | 0.000 | 0.003 | 0.001 | |
Hospitalizations/patient/year (range) | 1.2 ± 1.7 (0–6) | 0 | 0.1 ± 0.3 (0–1) | 0.049 |