Skip to main content

Table 5 The association of SNPs in ILVBL gene with the risk of AERD and % decline of FEV1 after adjusting rs1468198

From: Association analysis of ILVBL gene polymorphisms with aspirin-exacerbated respiratory disease in asthma

The risk of AERD
SNP OR [95% CI] P* Pcorr
rs13301 1.16 [0.55–2.41] 0.699 1.000
rs2074261 0.99 [0.47–2.09] 0.975 1.000
rs7507755 0.78 [0.52–1.17] 0.226 1.000
rs2240299 0.78 [0.52–1.16] 0.220 1.000
rs2074265 1.24 [0.94–1.61] 0.123 1.000
rs718100 1.24 [0.95–1.63] 0.109 1.000
rs4141356 1.18 [0.91–1.53] 0.222 1.000
rs2074267 0.96 [0.72–1.28] 0.772 1.000
% decline of FEV1
SNP β (± SE) P** Pcorr
rs13301 1.08 ± 1.25 0.387 1.000
rs2074261 0.06 ± 1.29 0.964 1.000
rs7507755 −0.64 ± 0.69 0.353 1.000
rs2240299 −0.65 ± 0.69 0.344 1.000
rs2074265 0.34 ± 0.51 0.505 1.000
rs718100 0.31 ± 0.51 0.535 1.000
rs4141356 0.19 ± 0.49 0.702 1.000
rs2074267 0.12 ± 0.52 0.814 1.000
  1. *, ** P values were obtained using logistic and linear regression analysis, respectively, controlling age of onset, smoking status, BMI, and genotype of rs1468198as covariates
  2. † Corrected P values for multiple comparison using SNPSpD
  3. OR odd ratio, CI confidence interval, SE standard error