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Table 2 Perioperative plasma HNPs 1–3 and inflammatory cytokines levels

From: Plasma levels of alarmin HNPs 1–3 associate with lung dysfunction after cardiac surgery in children

Variables

Before CPB

After CPB

1 h after CPB

12 h after CPB

24 h after CPB

HNPs 1–3 (ng/ml)

32.5 ± 44

224.9 ± 100.4a

220.4 ± 91.3b

85.6 ± 58.3c,d

37.7 ± 35.6e

IL-6 (pg/ml)

3.5 ± 6.3

17 ± 16.2a

68.3 ± 52.7b,g

139.7 ± 101c,d

136.2 ± 71.5e,f

IL-8 (pg/ml)

14.3 ± 6.1

37.8 ± 26.3

82.9 ± 70.5h,k

29 ± 17.5i

26 ± 14.6j

IL-10 (pg/ml)

24.2 ± 22.2

400.7 ± 236.5a

1525.7 ± 646.8b,g

66.4 ± 43.3c,d

32.1 ± 16.5e

  1. Data are presented as mean ± SD
  2. a P < 0.001 after CPB versus before CPB;
  3. b P < 0.001 1 h after CPB versus before CPB;
  4. c P < 0.001 12 h after CPB versus before CPB;
  5. d P < 0.001 12 h after CPB versus after CPB;
  6. e P < 0.001 24 h after CPB versus after CPB;
  7. f P < 0.001 24 h after CPB versus before CPB;
  8. g P < 0.001 1 h after CPB versus after CPB;
  9. h P = 0.002 1 h after CPB versus before CPB;
  10. i P = 0.007 12 h after CPB versus before CPB;
  11. j P = 0.01 24 h after CPB versus before CPB;
  12. k P < 0.03 1 h after CPB versus after CPB
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BMC Pulmonary Medicine

ISSN: 1471-2466

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