| Outcome variablea |
---|
| | FVC % | FEV1% | FEV1/FVC % | FEF 25–75%/FVC |
---|
Predictor | n | b | 95% CI | F-test p | b | 95% CI | F-test p | b | 95% CI | F-test p | b | 95% CI | F-test p |
---|
Weight SDS |
Birth–3 months | 356 | 0.26 | (−0.84, 1.36) | 0.642 | 0.32 | (−0.71, 1.35) | 0.540 | −0.01 | (−0.74, 0.72) | 0.974 | −0.28 | (−2.51, 1.96) | 0.808 |
BMI SDS |
3–6 months | 345 | 0.84 | (−0.94, 2.62) | 0.356 | 0.50 | (−1.17, 2.17) | 0.557 | −0.47 | (−1.65, 0.71) | 0.434 | −1.07 | (−4.66, 2.52) | 0.557 |
6–12 months | 344 | 0.89 | (−0.77, 2.55) | 0.292 | 0.02 | (−1.54, 1.58) | 0.980 | −0.83 | (−1.94, 0.29) | 0.145 | −1.71 | (−5.10, 1.68) | 0.321 |
1–4 years | 303 | 1.82 | (0.27, 3.36) |
0.021
| 1.82 | (0.36, 3.29) |
0.015
| −0.08 | (−1.13, 0.98) | 0.884 | 0.11 | (−3.06, 3.28) | 0.945 |
4–10.8/11.8 yearsb, c | 303 | 2.81 | (1.47, 4.15) |
<0.001
| 1.21 | (−0.08, 2.50) | 0.065 | −1.64 | (−2.57, −0.72) |
0.001
| −3.31 | (−6.13, −0.49) |
0.021
|
10.8/11.8c − 12.8 yearsd | 351 | 0.33 | (−1.42, 2.07) | 0.712 | −0.26 | (−1.95, 1.43) | 0.761 | −0.62 | (−1.81, 0.57) | 0.308 | −2.52 | (−6.21, 1.17) | 0.180 |
- Statistically significant p-values are indicated in bold numbers
- Abbreviations: FVC % forced vital capacity in percent of predicted, FEV1% forced expiratory volume in first second in percent of predicted, FEV1/FVC % Ratio of FEV over FVC in percent of predicted, FEF
25–75%
/FVC forced expiratory flow between 25% and 75% of the forced vital capacity over FVC given as a percentage; n: number of participants, b regression coefficient, CI Confidence interval, BMI body mass index (kg/m2), SDS standard deviation score, F-test p refers to exposure only
- aModel adjusted for sex, body size at start of interval, birth order, gestational age, duration of breastfeeding (none, < 3 months, > 3 months) (not for weight SDS at birth, and for BMI SDS at 3 months), preeclampsia (none/mild or moderate/severe), maternal BMI and maternal smoking at first antenatal visit (yes/no), maternal age, maternal asthma, maternal education
- bAlso adjusted for physical activity at 3–6 years
- c10.8/11.8 (girls/boys) years of age
- dAlso adjusted for physical activity at 6–10 years of age