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Table 5 Summary of adjusted linear regression analyses of lung function at 12.8 years in 463 Norwegian children according to change in weight and BMI SDS

From: The associations between weight-related anthropometrics during childhood and lung function in late childhood: a retrospective cohort study

 

Outcome variablea

  

FVC %

FEV1%

FEV1/FVC %

FEF 25–75%/FVC

Predictor

n

b

95% CI

F-test p

b

95% CI

F-test p

b

95% CI

F-test p

b

95% CI

F-test p

Weight SDS

 Birth–3 months

356

0.26

(−0.84, 1.36)

0.642

0.32

(−0.71, 1.35)

0.540

−0.01

(−0.74, 0.72)

0.974

−0.28

(−2.51, 1.96)

0.808

BMI SDS

 3–6 months

345

0.84

(−0.94, 2.62)

0.356

0.50

(−1.17, 2.17)

0.557

−0.47

(−1.65, 0.71)

0.434

−1.07

(−4.66, 2.52)

0.557

 6–12 months

344

0.89

(−0.77, 2.55)

0.292

0.02

(−1.54, 1.58)

0.980

−0.83

(−1.94, 0.29)

0.145

−1.71

(−5.10, 1.68)

0.321

 1–4 years

303

1.82

(0.27, 3.36)

0.021

1.82

(0.36, 3.29)

0.015

−0.08

(−1.13, 0.98)

0.884

0.11

(−3.06, 3.28)

0.945

 4–10.8/11.8 yearsb, c

303

2.81

(1.47, 4.15)

<0.001

1.21

(−0.08, 2.50)

0.065

−1.64

(−2.57, −0.72)

0.001

−3.31

(−6.13, −0.49)

0.021

 10.8/11.8c − 12.8 yearsd

351

0.33

(−1.42, 2.07)

0.712

−0.26

(−1.95, 1.43)

0.761

−0.62

(−1.81, 0.57)

0.308

−2.52

(−6.21, 1.17)

0.180

  1. Statistically significant p-values are indicated in bold numbers
  2. Abbreviations: FVC % forced vital capacity in percent of predicted, FEV1% forced expiratory volume in first second in percent of predicted, FEV1/FVC % Ratio of FEV over FVC in percent of predicted, FEF 25–75% /FVC forced expiratory flow between 25% and 75% of the forced vital capacity over FVC given as a percentage; n: number of participants, b regression coefficient, CI Confidence interval, BMI body mass index (kg/m2), SDS standard deviation score, F-test p refers to exposure only
  3. aModel adjusted for sex, body size at start of interval, birth order, gestational age, duration of breastfeeding (none, < 3 months, > 3 months) (not for weight SDS at birth, and for BMI SDS at 3 months), preeclampsia (none/mild or moderate/severe), maternal BMI and maternal smoking at first antenatal visit (yes/no), maternal age, maternal asthma, maternal education
  4. bAlso adjusted for physical activity at 3–6 years
  5. c10.8/11.8 (girls/boys) years of age
  6. dAlso adjusted for physical activity at 6–10 years of age