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Table 2 History of comorbidities and the Charlson Comorbidity Index (CCI) values at baseline

From: Exacerbations and healthcare resource utilization among COPD patients in a Swedish registry-based nation-wide study

Comorbidity variablea Female
N = 47,487 (53.6%)
Male
N = 41,061 (46.4%)
P-value Total
N = 88,548 (100%)
Cardiovascular disease 18,430 (38.8) 20,575 (50.1) <0.001 39,005 (44.0)
Hypertension 18,519 (39.0) 16,069 (39.1) 0.683 34,588 (39.1)
Asthma 11,782 (24.8) 7593 (18.5) <0.001 19,375 (21.9)
Any malignancy 8209 (17.3) 8325 (20.3) <0.001 16,534 (18.7)
Diabetes 7294 (15.4) 8012 (19.5) <0.001 15,306 (17.3)
Cerebrovascular disease 6248 (13.2) 6785 (16.5) <0.001 13,033 (14.7)
Mood disorders 4818 (10.1) 2526 (6.2) <0.001 7344 (8.3)
Osteoporosis 4688 (9.9) 845 (2.1) <0.001 5533 (6.2)
Renal disease 1304 (2.7) 2074 (5.1) <0.001 3378 (3.8)
Number of comorbidities
(from those listed above)
1.71 ± 1.37 1.77 ± 1.35 <0.001 1.74 ± 1.36
 0 10,233 (21.6) 8125 (19.8)   18,358 (20.7)
 1 13,210 (27.8) 10,948 (26.7) 24,158 (27.3)
 2 11,244 (23.7) 10,259 (25.0) 21,503 (24.3)
 3-5 12,454 (26.2) 11,513 (28.0) 23,967 (27.1)
 6-9 346 (0.7) 216(0.5) 562 (0.6)
CCI 2.5 ± 1.9 2.9 ± 2.1 <0.001 2.7 ± 2.0
 1 18,761 (39.5) 12,850 (31.3)   31,611 (35.7)
 2 10,338 (21.8) 8569 (20.9) 18,907 (21.4)
 3-5 15,066 (31.7) 15,452 (37.6) 30,518 (34.5)
  > 5 3322 (7.0) 4190 (10.2) 7512 (8.5)
Pneumonia/influenzab 2447 (5.2) 2481 (6.0) <0.001 4928 (5.6)
  1. Numbers presented as N (%), or mean ± SD. P-value for difference in mean values between genders
  2. Abbreviations: SD Standard deviation, CCI Charlson Comorbidity Index [8, 9]
  3. aVariable definitions are described at ICD-10 code level in Additional file 1: Table S1
  4. bEvaluated during previous year