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Table 6 Severe exacerbations and healthcare resource utilizations stratified in COPD patients stratified by resource use status with 4 categories

From: Exacerbations and healthcare resource utilization among COPD patients in a Swedish registry-based nation-wide study

High resource usea N of patients Person years N of events Crude rates Crude RR Adjustedb RR
Severe exacerbations
 No, No 51,384 48,270 6764 0.14 ref. ref.
 No, Yes
 Yes, No
 Yes, Yes
32,269
1838
3057
30,516
1465
2521
8758
2341
5293
0.29
1.60
2.10
2.05
11.40
14.98
2.07
10.35
13.46
Healthcare resource utilization
 No, No 51,384 48,270 179,149 3.71 ref. ref.
 No, Yes
 Yes, No
 Yes, Yes
32,269
1838
3057
30,516
1465
2521
119,372
12,002
18,976
3.91
8.19
7.53
1.05
2.21
2.03
1.12
1.89
1.95
  1. Abbreviation: RR Relative ratio
  2. aCategorical variable with 4 combinations of the following two variables: history of respiratory hospitalizations (≥2 within 1 year), and current medication use of ICS and LABA and/or LAMA (within 4 months). Categories (No/No, No/Yes, Yes/No, Yes/Yes)
  3. bAdjusted for age, gender, time since diagnosis, and Charlson comorbidity index