Table 1 Descriptive statistics of the COPD derivation and validation cohorts
From: Predictors of one-year mortality after hospitalization for an exacerbation of COPD
Derivation n = 1420 | Validation n = 3949 | p-value | |
|---|---|---|---|
Agea | 73.4 (10.0) | 72.7 (10.7) | 0.07 |
Sex (% male) | 1275 (89.8) | 3375 (85.5) | < 0.0001 |
FEV1% | 45.2 (16.2) | 45.3 (16.6) | 0.76 |
FEV1%/FVC | 52.5 (13.4) | 52.5 (12.9) | 0.79 |
FEV1% categories | < 0.0001 | ||
≥ 80% | 33 (3.8) | 62 (2.5) | |
< 80 - > 50 | 272 (31.2) | 778 (31.0) | |
< 50 - > 30 | 217 (24.3) | 1187 (47.3) | |
≤ 30 | 351 (40.2) | 482 (19.2) | |
Body Mass Indexa | 27.9 (5.3) | 27.8 (5.7) | 0.35 |
Smoking habit | 0.34 | ||
- Ever smoker | 52 (4.3) | 182 (4.9) | |
- Current smoker | 343 (28.2) | 977 (26.3) | |
- Ex-smoker | 822 (67.5) | 2554 (68.8) | |
Cigarette pack-yearsa | 55,82 (29.0) | 51,99 (30.3) | 0.003 |
Charlson Comorbidity Indexa | 2,70 (1.8) | 1,79 (1.7) | < 0.0001 |
1–2 | 795 (56.0) | 2865 (72.5) | |
≥ 3 | 625 (44.0) | 1084 (27.4) | |
Ischaemic heart disease | 205 (15.7) | 505 (12.8) | 0.008 |
Cardiac failure | 299 (23.0) | 810 (20.5) | 0.07 |
Peripheral vascular disease | 221 (17.2) | 494 (12.5) | < 0.0001 |
Cerebrovascular disease | 146 (11.3) | 380 (9.6) | 0.09 |
Cardiac-Cerebro-Peripheral vascular disease | 608 (46.2) | 2217 (44.9) | 0.41 |
Dementia | 138 (3,49) | 52 (4,04) | 0.36 |
Diabetes mellitus | 359 (26.2) | 1032 (26.1) | 0.95 |
Previous COPD hospitalization | 1065 (76.7) | 1881 (51.3) | < 0.0001 |
Mean of COPD-related admissions in the previous year | 1.92 (2.0) | 1.17 (1.8) | < 0.0001 |
pH at arrival | 7.40 (0.1) | 7.40 (0.1) | 0.12 |
Acidaemia during admission | 258 (19.3) | NA | |
PaO2 at arrivala | 59.1 (15.6) | 60.4 (21.3) | 0.79 |
PaCO2 at arrivala | 47.2 (14.4) | 48.4 (15.7) | 0.074 |
Length of staya | 10.1 (6.9) | 9.3 (7.0) | < 0.0001 |