TY - JOUR AU - Bräunlich, Jens AU - Mauersberger, Friederike AU - Wirtz, Hubert PY - 2018 DA - 2018/01/24 TI - Effectiveness of nasal highflow in hypercapnic COPD patients is flow and leakage dependent JO - BMC Pulmonary Medicine SP - 14 VL - 18 IS - 1 AB - Nasal Highflow (NHF) delivers a humidified and heated airflow via nasal prongs. Current data provide evidence for efficacy of NHF in patients with hypoxemic respiratory failure. Preliminary data suggest that NHF may decrease hypercapnia in hypercapnic respiratory failure. The aim of this study was to evaluate the mechanism of NHF mediated PCO2 reduction in patients with chronic obstructive pulmonary disease (COPD). SN - 1471-2466 UR - https://doi.org/10.1186/s12890-018-0576-x DO - 10.1186/s12890-018-0576-x ID - Bräunlich2018 ER -