Table 2 Changes of mean airway pressure and PCO2 in patients with baseline PCO2 > 55 mmHg under different experimental conditions
From: Effectiveness of nasal highflow in hypercapnic COPD patients is flow and leakage dependent
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Condition | A | B | C | D |
Mechanically gene-rated flow rate (L/min) | 20 | 40 | 40 | 40 |
Effective nasal flow rate (L/min) | 20 | 40 | 20 | 40 |
Mean airway pressure (mbar ± SD) | 0.57 ± 0.38 p = 0.03 | 2.3 ± 1.6 p = 0.02 | 1.63 ± 1.4 p = 0.08 | 2.13 ± 1.7 p = 0.05 |
PO2 (% baseline PO2 ± SD) | 99.2 ± 18.9 p = 0.2 | 93.1 ± 15.7 p = 0.18 | 93.8 ± 17.6 p = 0.12 | 93.5 ± 11.9 p = 0.05 |
PCO2 (% baseline PCO2 ± SD) | 94.2 ± 8.3 p = 0.01 | 93.5 ± 4.4 p = 0.000 | 90.5 ± 7.2 p = 0.005 | 86.8 ± 3.8 p = 0.001 |
