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Table 5 Parameters of respiratory pump function, exercise capacity and biomarkers

From: Heterogeneous pattern of differences in respiratory parameters between elderly with either good or poor FEV1

Parameter

UED group

LED group

Mean difference (UED-LED)

95% CI of difference

p-value for difference

Number

Mean ± SD

Median (25%; 75%)

Number

Mean ± SD

Median (25%; 75%)

lower

upper

PImax %pred

66

102.9 ± 34.0

100.7 (81.5; 123.2)

50

91.9 ± 31.9

90.9 (70.4; 111.0)

11.0

−1.3

23.3

0.079

log10(P01, kPa)

66

−0.72 ± 0.22

− 0.69 (− 0.89; − 0.55)

50

−0,53 ± 0,20

−0.53 (− 0.64; − 0.41)

−0.19

− 0.27

−0.11

< 0.001

log10(P01/PImax)

66

−1.57 ± 0.27

−1.52 (− 1.74; − 1.41)

50

−1.34 ± 0.30

−1.34 (− 1.54; − 1.12)

− 0.22

− 0.33

− 0.12

< 0.001

6MWD %pred

71

113.0 ± 17.9

114.2 (98.8; 126.1)

51

98.9 ± 21.1

101.4 (91.1; 112.4)

14.1

6.9

21.4

< 0.001

PRE Dyspnoea

60

0.06 ± 0.21

0.00 (0.00; 0.00)

49

0.51 ± 0.92

0.00 (0.00; 1.00)

− 0.45

−0.72

− 0.18

0.001

POST Dyspnoea

60

1.63 ± 1.51

1.00 (0.50; 3.00)

49

2.62 ± 1.78

3.00 (1.00; 4.00)

−1.00

− 1.63

−0.36

0.002

PRE Fatigue

60

0.26 ± 0.61

0.00 (0.00; 0.00)

49

0.62 ± 0.97

0.00 (0.00; 1.00)

−0.36

−0.68

− 0.05

0.025

POST Fatigue

60

0.61 ± 1.20

0.00 (0.00; 0.88)

49

1.09 ± 1.30

0.50 (0.00; 2.00)

−0.48

−0.96

− 0.01

0.048

eCO, ppm

72

3.5 ± 1.3

3.0 (3.0; 4.0)

51

4.4 ± 1.2

4.0 (3.0; 5.0)

−0.8

−1.3

−0.4

< 0.001

log10(FeNO, ppb)

72

1.305 ± 0.164

1.306 (1.206; 1.422)

51

1.334 ± 0.222

1.317 (1.179; 1.508)

−0.029

−0.102

0.044

0.433

serum 8-OHdG, ng/mL

72

0.181 ± 0.065

0.186 (0.129; 0.228)

50

0.178 ± 0.065

0.180 (0.144; 0.212)

0.002

−0.022

0.026

0.845

Telomere length, T/S ratio

72

1.562 ± 0.244

1.564 (1.412; 1.699)

50

1.489 ± 0.179

1.472 (1.344; 1.609)

0.073

−0.003

0.149

0.058

  1. Reference values were calculated according to Enright et al. [16] for PImax and according to Enright and Sherrill [17] for 6MWD
  2. p-values below 0.05 are shown in bold