Parameter | UED group | LED group | Mean difference (UED-LED) | 95% CI of difference | p-value for difference | |||||
---|---|---|---|---|---|---|---|---|---|---|
Number | Mean ± SD | Median (25%; 75%) | Number | Mean ± SD | Median (25%; 75%) | lower | upper | |||
PImax %pred | 66 | 102.9 ± 34.0 | 100.7 (81.5; 123.2) | 50 | 91.9 ± 31.9 | 90.9 (70.4; 111.0) | 11.0 | −1.3 | 23.3 | 0.079 |
log10(P01, kPa) | 66 | −0.72 ± 0.22 | − 0.69 (− 0.89; − 0.55) | 50 | −0,53 ± 0,20 | −0.53 (− 0.64; − 0.41) | −0.19 | − 0.27 | −0.11 | < 0.001 |
log10(P01/PImax) | 66 | −1.57 ± 0.27 | −1.52 (− 1.74; − 1.41) | 50 | −1.34 ± 0.30 | −1.34 (− 1.54; − 1.12) | − 0.22 | − 0.33 | − 0.12 | < 0.001 |
6MWD %pred | 71 | 113.0 ± 17.9 | 114.2 (98.8; 126.1) | 51 | 98.9 ± 21.1 | 101.4 (91.1; 112.4) | 14.1 | 6.9 | 21.4 | < 0.001 |
PRE Dyspnoea | 60 | 0.06 ± 0.21 | 0.00 (0.00; 0.00) | 49 | 0.51 ± 0.92 | 0.00 (0.00; 1.00) | − 0.45 | −0.72 | − 0.18 | 0.001 |
POST Dyspnoea | 60 | 1.63 ± 1.51 | 1.00 (0.50; 3.00) | 49 | 2.62 ± 1.78 | 3.00 (1.00; 4.00) | −1.00 | − 1.63 | −0.36 | 0.002 |
PRE Fatigue | 60 | 0.26 ± 0.61 | 0.00 (0.00; 0.00) | 49 | 0.62 ± 0.97 | 0.00 (0.00; 1.00) | −0.36 | −0.68 | − 0.05 | 0.025 |
POST Fatigue | 60 | 0.61 ± 1.20 | 0.00 (0.00; 0.88) | 49 | 1.09 ± 1.30 | 0.50 (0.00; 2.00) | −0.48 | −0.96 | − 0.01 | 0.048 |
eCO, ppm | 72 | 3.5 ± 1.3 | 3.0 (3.0; 4.0) | 51 | 4.4 ± 1.2 | 4.0 (3.0; 5.0) | −0.8 | −1.3 | −0.4 | < 0.001 |
log10(FeNO, ppb) | 72 | 1.305 ± 0.164 | 1.306 (1.206; 1.422) | 51 | 1.334 ± 0.222 | 1.317 (1.179; 1.508) | −0.029 | −0.102 | 0.044 | 0.433 |
serum 8-OHdG, ng/mL | 72 | 0.181 ± 0.065 | 0.186 (0.129; 0.228) | 50 | 0.178 ± 0.065 | 0.180 (0.144; 0.212) | 0.002 | −0.022 | 0.026 | 0.845 |
Telomere length, T/S ratio | 72 | 1.562 ± 0.244 | 1.564 (1.412; 1.699) | 50 | 1.489 ± 0.179 | 1.472 (1.344; 1.609) | 0.073 | −0.003 | 0.149 | 0.058 |