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Table 2 Comparison of HRCT findings in patients with SSc-associated ILD

From: Emphysematous change with scleroderma-associated interstitial lung disease: the potential contribution of vasculopathy?

Characteristics

All subjects

Existence of pathological pulmonary emphysema

P value

Yes (p-PE with SSc-ILD)

No

HRCT pattern N (%)

 Suggestive of UIP

2 (9.5)

2 (12.5)

0 (0.0)

> 0.999

 Suggestive or consistent with NSIP

19 (90.5)

14 (87.5)

5 (100.0)

HRCT findings N (%)

 GGO

21 (100.0)

16 (100.0)

5 (100.0)

N/A

 Consolidation

2 (9.5)

1 (6.3)

1 (20.0)

0.429

 Reticulation

21 (100.0)

16 (100.0)

5 (100.0)

N/A

 Honeycombing

1 (4.8)

1 (6.3)

0 (0.0)

> 0.999

 Traction bronchiectasis

20 (95.2)

16 (100.0)

4 (80.0)

0.238

 Bronchial wall thickening

10 (47.6)

7 (43.8)

3 (60.0)

0.635

 Micro-nodules

3 (14.3)

3 (18.7)

0 (0.0)

0.549

 Emphysema (LAA around no fibrotic appearance)

4 (19.0)

3 (18.7)

1 (20.0)

> 0.999

 LAA within interstitial abnormalities

5 (23.8)

5 (31.3)

0 (0.0)

0.278

 Cyst (non-honeycombing, emphysema)

5 (23.8)

4 (25.0)

1 (20.0)

> 0.999

 Mosaic attenuation (air trapping)

7 (33.3)

4 (25.0)

3 (60.0)

0.280

 Enlarged mediastinal lymph node

4 (19.0)

3 (18.7)

1 (20.0)

> 0.999

 Pleural thickening or effusion

3 (14.3)

3 (18.7)

0 (0.0)

0.549

 Pulmonary artery dilatation

6 (28.6)

5 (31.3)

1 (20.0)

> 0.999

 Volume loss

17 (81.0)

14 (87.5)

3 (60.0)

0.228

  1. Data are presented as mean ± SD, unless otherwise stated. SSc systemic sclerosis, ILD interstitial lung disease, p-PE pathological pulmonary emphysema, HRCT high-resolution computed tomography, UIP usual interstitial pneumonia, NSIP nonspecific interstitial pneumonia, GGO ground glass opacity