Emphysematous change with scleroderma-associated interstitial lung disease: the potential contribution of vasculopathy?

Table 4 Characteristics of the 21 patients with SSc-associated ILD

Patient	Sex	HRCT findings		Pathological findings		Pulmonary vascular change
Patient	Sex	Disease extent, %	LAA within the interstitial abnormalities	Classification	Emphysema, (grading score)	Muscular type, (grading score)	Arteriole	Venule	Interlobular vein
1	Female	41.37	+	fNSIP	2	1	+	+	+
2	Female	38.24	None	fNSIP	2	1	+	+	+
3	Female	42.37	+	fNSIP	1	2	+	+	+
4	Female	17.54	+	fNSIP	1	1	+	+	+
5	Female	13.65	None	Unclassifiable	1	1	+	+	+
6	Female	33.2	None	fNSIP	1	0	+	+	+
7	Female	13.47	None	fNSIP	1	0	+	+	–
8	Male	25.77	+	fNSIP	2	0	+	–	+
9	Female	18.86	None	fNSIP	1	0	+	+	+
10	Male	29.37	None	fNSIP	1	1	–	+	+
11	Female	N/A	None	fNSIP	1	2	+	+	+
12	Female	42.31	+	fNSIP	2	1	+	–	+
13	Female	16.7	None	fNSIP	1	1	+	+	–
14	Female	23.1	None	fNSIP	1	2	+	+	+
15	Female	36.22	None	Unclassifiable	1	2	+	+	+
16	Female	29.78	None	fNSIP	1	2	+	+	+
17	Female	19.58	None	fNSIP	0	0	+	+	+
18	Female	12.03	None	fNSIP	0	0	–	+	–
19	Male	13.3	None	fNSIP	0	2	+	–	+
20	Female	15.27	None	Unclassifiable	0	0	+	+	+
21	Female	16.55	None	fNSIP	0	0	+	+	–

SSc systemic sclerosis, ILD interstitial lung disease, HRCT high-resolution computed tomography, LAA low attenuation area, fNSIP fibrotic nonspecific interstitial pneumonia, N/A not applicable

ISSN: 1471-2466