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Table 1 Burkholderia Eradication Protocol

From: Implementation of a successful eradication protocol for Burkholderia Cepacia complex in cystic fibrosis patients

  Medication Dosing Frequency Route Bacteria Targeted
Induction Period (21 Days): Tobramycin 6 mg/kg (per kinetics) Daily IV PsA, Bcc
Ceftazidime 2 g Every 8 h IV PsA, Bcc
Trimethoprim/Sulfamethoxazole 800/160 mg Twice Daily Oral Bcc
Tobramycin inhaleda 300 mg Twice Daily Nebulized PsA, Bcc
Azithromycin 250 mg Daily Oral Anti-inflammatory
Consolidation Period (2 months): Trimethoprim/Sulfamethoxazole 800/160 mg Twice daily Oral Bcc
Tobramycin inhaleda 300 mg Twice daily Nebulized PsA, Bcc
Azithromycin 250 mg Daily Oral Anti-inflammatory
  1. aAlternative- TIP (tobramycin dry powder for inhalation, 4 caps (28 mg/cap)) every 12 h