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Table 2 UIP Cohort Treatment Exposure During Study Period

From: N-acetylcysteine exposure is associated with improved survival in anti-nuclear antibody seropositive patients with usual interstitial pneumonia

Therapy NAC Exposed (n = 58) NAC Unexposed (n = 235) p-value
NAC monotherapy 29 (50) 0 (0) < 0.001
Immunosuppressant exposurea 15 (25.9) 54 (22.8) 0.64
 Prednisone 15 (25.9) 53 (22.6) 0.59
 Azathioprine 8 (13.8) 9 (3.8) 0.004
 Mycophenolate mofetil 3 (6.0) 3 (2.8) 0.38
Anti-fibrotic exposure 11 (18.9) 29 (12.3) 0.19
 Pirfenidone 10 (17.2) 24 (10.2) 0.13
 Nintedanib 1 (1.8) 6 (2.6) 1
  1. Abbreviations: UIP usual interstitial pneumonia, NAC N-acetylcysteine
  2. aAzathioprine/prednisone or mycophenolate/prednisone