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Table 2 Factors related to unsuccessful treatment outcome among northern Ethiopian prisoners with tuberculosis in the bivariate and multivariate logistic regression analysis (n = 422). AOR: adjusted odds ratio; COR: crude odds ratio; CI: confidence interval; ref = reference

From: Tuberculosis treatment outcome and predictors in northern Ethiopian prisons: a five-year retrospective analysis

Characteristic Treatment outcome COR (95% CI) P-value AOR (95% CI) P-value
Unsuccessful
n (%)
Successful
n (%)
Sex
 Female 2 (14.3) 12 (85.7) 2.56 (0.54-12.04) 0.26 -  
 Male 25 (6.2) 383 (93.8) ref    
Age, years
 15-24 8 (4.6) 164 (95.4) 0.62 (0.23-1.71) 0.36 -  
 25-34 11 (7.9) 129 (92.1) 0.86 (0.86-1.09)    
> 35 8 (7.3) 102 (92.7) ref    
Weight at initiation (Kg)
 < 50 15 (8.4) 164 (91.6) 1.76 (0.83-3.86)   1.72 (0.75-3.98) 0.2
> 50 12 (4.9) 231 (95.1) ref    
Form of TBa
 PTB+ 8 (7.6) 97 (92.3) 1.22 (0.48-3.14) 0.48 -  
 PTB - 8 (6.1) 124 (93.9) 0.96 (0.37-2.45) 0.38   
 EPTP 11 (6.3) 163 (93.7) ref    
Non-conversion at the 2nd monthb
 Yes 2 (12.5) 4 (87.5) 9.1 (1.33-62.16) 0.02 -  
 No 5 (5.2) 91 (94.8)     
Type of TB case
 Retreatment case 3 (25.0) 9 (75.0) 5.36 (1.36-21.11) 0.01 4.68 (1.02-21.4) 0.04
 New case 24 (5.8) 386 (94.2) ref    
HIV statusC
 Positive 4 (8.5) 43 (91.5) 1.36 (0.45-4.14) 0.58 -  
 Negative 23 (6.4) 338 (93.6) ref    
Year
 Sep 2010-Aug 2011 10 (13.3) 65 (86.7) ref    
 Sep 2011-Aug 2012 5 (5.8) 81 (93.2) 0.41 (0.13-1.23) 0.11 0.28 (0.08-0.92) 0.04
 Sep 2012-Aug 2013 3 (4.2) 69 (95.8) 0.28 (0.07-1.07) 0.06 0.24 (0.06-0.98) 0.047
 Sep 2013-Aug 2014 3 (3.0) 97 (97.0) 0.21(0.05-0.76) 0.018 0.17 (0.05-0.67) 0.01
 Sep 2014-Aug 2015 6 (6.7) 83 (93.3) 0.48 (0.16-1.36) 0.16 0.45 (0.14-1.43) 0.18
Site
 Mekelle 12 (8.6) 127 (91.4) ref    
 Alamata 1 (1.4) 72 (98.6) 0.15 (0.02-1.15) 0.07 0.14 (0.02-1.18) 0.07
 Shire 5 (6.8) 68 (93.2) 0.78 (0.26-2.30) 0.65 0.53 (0.16-169) 0.28
 Humera 9 (6.6) 128 (93.4) 0.74 (0.3-1.83) 0.52 0.64 (0.23-1.72) 0.38
  1. aPatients with both PTB & EPTB were not included; bAnalysis limited to the smear-positive cases; cAnalysis limited to patients with known HIV status; HIV human immunodeficiency virus; Kg kilogram; PTB+ smear-positive pulmonary tuberculosis; PTB- smear-negative pulmonary tuberculosis; EPTB extra-pulmonary tuberculosis