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Table 2 Factors related to unsuccessful treatment outcome among northern Ethiopian prisoners with tuberculosis in the bivariate and multivariate logistic regression analysis (n = 422). AOR: adjusted odds ratio; COR: crude odds ratio; CI: confidence interval; ref = reference

From: Tuberculosis treatment outcome and predictors in northern Ethiopian prisons: a five-year retrospective analysis

Characteristic

Treatment outcome

COR (95% CI)

P-value

AOR (95% CI)

P-value

Unsuccessful

n (%)

Successful

n (%)

Sex

 Female

2 (14.3)

12 (85.7)

2.56 (0.54-12.04)

0.26

-

 

 Male

25 (6.2)

383 (93.8)

ref

   

Age, years

 15-24

8 (4.6)

164 (95.4)

0.62 (0.23-1.71)

0.36

-

 

 25-34

11 (7.9)

129 (92.1)

0.86 (0.86-1.09)

   

 > 35

8 (7.3)

102 (92.7)

ref

   

Weight at initiation (Kg)

 < 50

15 (8.4)

164 (91.6)

1.76 (0.83-3.86)

 

1.72 (0.75-3.98)

0.2

 > 50

12 (4.9)

231 (95.1)

ref

   

Form of TBa

 PTB+

8 (7.6)

97 (92.3)

1.22 (0.48-3.14)

0.48

-

 

 PTB -

8 (6.1)

124 (93.9)

0.96 (0.37-2.45)

0.38

  

 EPTP

11 (6.3)

163 (93.7)

ref

   

Non-conversion at the 2nd monthb

 Yes

2 (12.5)

4 (87.5)

9.1 (1.33-62.16)

0.02

-

 

 No

5 (5.2)

91 (94.8)

    

Type of TB case

 Retreatment case

3 (25.0)

9 (75.0)

5.36 (1.36-21.11)

0.01

4.68 (1.02-21.4)

0.04

 New case

24 (5.8)

386 (94.2)

ref

   

HIV statusC

 Positive

4 (8.5)

43 (91.5)

1.36 (0.45-4.14)

0.58

-

 

 Negative

23 (6.4)

338 (93.6)

ref

   

Year

 Sep 2010-Aug 2011

10 (13.3)

65 (86.7)

ref

   

 Sep 2011-Aug 2012

5 (5.8)

81 (93.2)

0.41 (0.13-1.23)

0.11

0.28 (0.08-0.92)

0.04

 Sep 2012-Aug 2013

3 (4.2)

69 (95.8)

0.28 (0.07-1.07)

0.06

0.24 (0.06-0.98)

0.047

 Sep 2013-Aug 2014

3 (3.0)

97 (97.0)

0.21(0.05-0.76)

0.018

0.17 (0.05-0.67)

0.01

 Sep 2014-Aug 2015

6 (6.7)

83 (93.3)

0.48 (0.16-1.36)

0.16

0.45 (0.14-1.43)

0.18

Site

 Mekelle

12 (8.6)

127 (91.4)

ref

   

 Alamata

1 (1.4)

72 (98.6)

0.15 (0.02-1.15)

0.07

0.14 (0.02-1.18)

0.07

 Shire

5 (6.8)

68 (93.2)

0.78 (0.26-2.30)

0.65

0.53 (0.16-169)

0.28

 Humera

9 (6.6)

128 (93.4)

0.74 (0.3-1.83)

0.52

0.64 (0.23-1.72)

0.38

  1. aPatients with both PTB & EPTB were not included; bAnalysis limited to the smear-positive cases; cAnalysis limited to patients with known HIV status; HIV human immunodeficiency virus; Kg kilogram; PTB+ smear-positive pulmonary tuberculosis; PTB- smear-negative pulmonary tuberculosis; EPTB extra-pulmonary tuberculosis