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Table 1 Recipients characteristics of patients with class I/II panel reactive antibody < 50% and ≥50%

From: Prevalence of pre-transplant anti-HLA antibodies and their impact on outcomes in lung transplant recipients

 

All recipients (n = 76)

PRA < 50% (n = 67)

PRA ≥ 50% (n = 9)

p-value

Age, median (range), yrs

52.0 (17–75)

53.0 (18–75)

44.0 (17–52)

0.013

Male, n (%)

42 (55.3)

39 (58.2)

3 (33.3)

0.284

BMI, median (IQR), kg/m2

19.1 (17.4–21.6)

19.0 (17.4–21.6)

19.8 (16.1–21.6)

0.981

ABO, n (%)

   

0.413

 A

26 (34.2)

24 (35.8)

2 (22.2)

 

 B

26 (34.2)

23 (34.3)

3 (33.3)

 

 AB

6 (7.9)

4 (6.0)

2 (22.2)

 

 O

18 (23.7)

16 (23.9)

2 (22.2)

 

Primary diagnosis, n (%)

   

0.277

 COPD/emphysema

4 (5.3)

3 (4.5)

1 (11.1)

 

 IPF

37 (48.7)

35 (52.2)

2 (22.2)

 

 IPAH

1 (1.3)

1 (1.5)

0 (0)

 

 IIP other than IPF*

3 (3.9)

2 (3.0)

1 (11.1)

 

 Bronchiectasis/ destroyed lung by TB

4 (5.3)

4 (6.0)

0 (0)

 

 BOS after HSCT

11 (14.5)

9 (14.9)

2 (22.2)

 

 Interstitial lung disease related with CTD

5 (6.6)

4 (6.0)

1 (11.1)

 

 LAM

9 (11.8)

7 (10.4)

2 (22.2)

 

 Others**

2 (2.6)

2 (3.0)

0 (0)

 

Smoking, n (%)

   

0.141

 Smoker

30 (39.5)

29 (43.3)

1 (11.1)

 

   ≥ 20 pack-years

22 (28.9)

21 (31.3)

1 (11.1)

 

   < 20 pack-years

8 (10.6)

8 (12.0)

0 (0)

 

  Never smoker

46 (60.5)

38 (56.7)

8 (88.9)

 

Bilateral lung transplantation, n (%)

62 (81.6)

53 (79.1)

9 (100)

0.197

  1. *NSIP and AIP were included
  2. **Others: diffuse panbronchiolitis, langerhans cell histiocytosis
  3. BMI, body mass index; COPD, chronic obstructive pulmonary disease; IPF, idiopathic pulmonary fibrosis; IPAH, Idiopathic pulmonary arterial hypertension; IIP, Idiopathic interstitial pneumonia; TB, tuberculosis; BOS, Bronchiolitis obliterans syndrome; CTD, connective tissue disease; LAM, Lymphangioleiomyomatosis; NSIP, non-specific interstitial pneumonia; AIP, acute interstitial pneumonia; HSCT, hematopoietic stem cell transplantation