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Table 3 Characteristics and examination results of COPD patients in acute exacerbation stage

From: Aspergillus fumigatus during COPD exacerbation: a pair-matched retrospective study

 

Aspergillus colonization, n = 23

Control,

n = 69

p value

Symptom and sign

 cough

20 (87.0%)

61 (88.4%)

1.000

 dyspnea

14 (60.9%)

53 (76.8%)

0.177

 wheezing

12 (52.2%)

11 (15.9%)

0.001

 fever

12 (52.2%)

28 (40.6%)

0.344

 moist rale

13 (56.5%)

27 (39.1%)

0.156

 wheezing rale

15 (65.2%)

26 (38.2%)

0.031

Blood routine

 WBC count (× 109/L)

6.45 ± 2.23

7.25 ± 3.57

0.319

 NEUT count (×109/L)

4.73 ± 2.07

4.94 ± 3.28

0.771

 NEUT% (%)

71.2 ± 13.2

65.7 ± 13.0

0.092

 EOS% < 0.5%

30.4%

23.2%

0.487

 EOS% > 5%

4.3%

23.2%

0.044

Arterial blood gas

 Pa/Fi

317 ± 42

324 ± 59

0.625

 pH

7.41 ± 0.03

7.38 ± 0.72

0.063

 PaCO2 (mmHg)

40.3 ± 6.3

44.5 ± 10.6

0.088

 PaO2 (mmHg)

70.5 ± 10.9

76.8 ± 15.5

0.102

Biomarker

 CRP (mg/dl)

3.23 ± 3.51

2.53 ± 3.12

0.412

 ESR (mm/h)

25.3 ± 28.2

20.0 ± 20.3

0.436

 Total IgE (IU/ml)

441 ± 1075

282 ± 362

0.386

  1. Italicized p-values are statistically significant, ie. p < 0.05