Table 2 Lung function by sex and pubertal stage in children 6–18 years with asthma
From: Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma
| Â | Males | Females | Females | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tanner stages of pubic hair†| Tanner stages of breast development†| Tanner stages of pubic hair†| ||||||||||
1–2 n = 84 | 3–5 n = 32 | Ratio 3–5:1–2 | ∆ 3–5:1–2 | 1–2 n = 32 | 3–5 n = 39 | Ratio 3–5:1–2 | ∆ 3–5:1–2 | 1–2 n = 37 | 3–5 n = 34 | Ratio 3–5:1–2 | ∆ 3–5:1–2 | |
Pre-BD FEV1 (%) | 89.4 ± 18.5 | 89.1 ± 16.4 | 1.00 | − 0.3 | 93.9 ± 13.0 | 87.2 ± 14.9 | 0.93 | −6.8 | 90.4 ± 15.2 | 90.1 ± 13.7 | 1.00 | − 0.3 |
Max Post-BD FEV1 (%) | 103.5 ± 19.3 | 105.7 ± 10.2 | 1.02 | 2.2 | 109.4 ± 13.1 | 100.5 ± 13.1 | 0.92 | − 8.9* | 106.0 ± 14.4 | 102.9 ± 13.0 | 0.97 | − 3.1 |
BD Resp. (% FEV1 change) | 17.3 ± 16.6 | 21.8 ± 20.8 | 1.26 | 4.5 | 17.2 ± 10.7 | 17.2 ± 17.5 | 1.00 | −0.0 | 19.1 ± 17.1 | 15.2 ± 11.5 | 0.80 | −3.9 |
Absolute BD Resp. (net FEV1 change) | 14.1 ± 10.3 | 16.7 ± 11.7 | 1.18 | 2.5 | 15.5 ± 8.3 | 13.4 ± 9.2 | 0.86 | −2.1 | 15.7 ± 9.7 | 12.9 ± 7.6 | 0.82 | −2.8 |
Pre-BD FVC (%) | 101.4 ± 15.9 | 106.4 ± 16.0 | 1.05 | 5.0 | 106.3 ± 11.6 | 100.5 ± 12.9 | 0.94 | −5.9* | 102.9 ± 13.5 | 103.3 ± 11.8 | 1.01 | 0.4 |
Max Post-BD FVC (%) | 109.2 ± 17.6 | 112.5 ± 13.8 | 1.03 | 3.3 | 113.8 ± 12.9 | 104.8 ± 13.7 | 0.92 | −9.0* | 110.4 ± 14.9 | 107.2 ± 13.0 | 0.97 | − 3.2 |
Pre-BD FEV1/FVC (%) | 87.3 ± 10.7 | 83.5 ± 11.6 | 0.96 | −3.8 | 87.9 ± 8.4 | 86.3 ± 10.9 | 0.98 | −1.5 | 87.2 ± 9.9 | 86.8 ± 9.9 | 1.00 | −0.4 |
Max Post-BD FEV1/FVC (%) | 94.9 ± 8.8 | 94.9 ± 7.4 | 1.00 | 0.0 | 97.2 ± 7.6 | 96.4 ± 8.2 | 0.99 | −0.8 | 97.1 ± 7.8 | 96.4 ± 8.1 | 0.99 | − 0.6 |
PC20 (log 2) | 0.3 ± 1.9 n = 35 | 1.0 ± 3.0 n = 10 | 3.57 | 0.7 | −0.7 ± 3.6 n = 7 | 0.0 ± 2.4 n = 15 | − 0.05 | 0.7 | − 0.3 ± 3.3 n = 10 | −0.1 ± 2.4 n = 12 | 0.47 | 0.2 |