| Adjusted OR | 95% CI | p-value |
---|---|---|---|
1. Socio-demographic factors | |||
 Age (Referenta: [18–39]) | |||
  [40–64] years | 0.75 | [0.38–1.49] | .414 |
   > 64 years | 0.77 | [0.21–2.76] | .683 |
Married | 2.37 | [0.63–8.85] | .201 |
Number of children (Referenta: ≤2) | 0.47 | [0.24–0.93] | .030* |
Educational level (Referenta: secondary or university) | 0.50 | [0.24–1.04] | .064 |
Health insurance | 0.41 | [0.18–0.93] | .033* |
2. Environmental and clinical factors | |||
 Smoking (Referenta: never smoker) | |||
  Active smoker | 0.51 | [0.19–1.39] | .191 |
  Ex smoker | 0.50 | [0.16–1.60] | .242 |
 Concomitant diseases | 3.36 | [0.99–11.34] | .050* |
 Co-morbidities | |||
 Rhinitis | 0.84 | [0.29–2.45] | .756 |
  Allergic conjunctivitis | 1.00 | [0.49–2.03] | 1.00 |
  Gastroesophageal Reflux Disease | 1.83 | [0.70–4.82] | .219 |
  Respiratory Infections | 5.71 | [2.39–13.63] | .000* |
 Allergy to animals | 2.76 | [1.36–5.59] | .005* |
 Adherence to treatment | 0.07 | [0.01–0.98] | .049* |