Table 3 Comparison of patients without (AHI < 5/h), with mild (AHI 5–15/h)or moderate to severe (AHI > 15/h) sleep-disordered breathing
From: Sleep-disordered breathing in patients with newly diagnosed lung cancer
AHI < 5/h | AHI 5–15/h | AHI > 15/h | p-value | |
|---|---|---|---|---|
n | 51 | 32 | 17 | N/A |
Age, years | 66.31 ± 8.48 | 69.16 ± 8.06 | 71.35 ± 8.775 | 0.0736 |
Male, n (%) | 30 (58.8) | 24 (75.0) | 13 (76.5) | 0.2062 |
BMI, kg/m2 | 25.53 ± 4.45 | 26,67 ± 4,95 | 26.41 ± 4.14 | 0.5133 |
AHI, /h | 2 [1, 3] | 7.7 [5.4, 10.4] | 25.2 [18, 45.5] | < 0.0001 |
ODI, /h | 3.1 [1.5, 5.1] | 8.5 [4.2, 13.4] | 20.6 [9.6, 36.6] | < 0.0001 |
Mean SpO2, % | 91.47 ± 2.56 | 91.09 ± 2.36 | 91.35 ± 2.14 | 0.7900 |
Time with SpO2 < 90%, min | 36 [8, 84] | 25.5 [8.3, 92.3] | 41 [10.5,63] | 0.9999 |
ESS score | 5.74 ± 3.53 | 6.22 ± 2.72 | 8.24 ± 3.96 | 0.0343 |
PSQI score | 6.49 ± 2.69 | 7.97 ± 3.97 | 6.71 ± 2.62 | 0.1137 |
Snoring, /h | 69 [19.6, 148] | 61.2 [26.8, 156.4] | 69 [30.5,89.7] | 0.9343 |
Histology, n (%) | ||||
SCLC | 14 (27.5) | 4 (12.5) | 5 (29.4) | 0.2280 |
NSCLC | 37 (72.5) | 28 (87.5) | 12 (70.6) | |
- Adenocarcinoma | 22 (43.1) | 18 (56.3) | 5 (29.4) | 0.7034 |
- Squamous cell carcinoma | 12 (23.5) | 7 (21.9) | 5 (29.4) | |
- Other | 3 (5.9) | 3 (9.4) | 2 (11.8) | |
Tumor stage (UICC), n (%) | ||||
I | 3 (5.9) | 4 (12.5) | 2 (11.8) | 0.1556 |
II | 5 (9.8) | 3 (9.4) | 5 (29.4) | |
III | 19 (37.3) | 7 (21.9) | 2 (11.8) | |
IV | 24 (47.1) | 18 (56.3) | 8 (47.1) | |
Smoking history, n (%) | ||||
Current smoker | 27 (52.9) | 14 (43.8) | 7 (41.2) | 0.8782 |
Ex-smoker | 16 (31.4) | 13 (40.6) | 7 (41.2) | |
Never smoked | 8 (15.7) | 5 (15.6) | 3 (17.6) | |
Comorbidities, n (%) | ||||
Hypertension | 26 (50.1) | 21 (65.6) | 9 (52.9) | 0.4088 |
Diabetes | 4 (7.8) | 6 (18.8) | 4 (23.5) | 0.1749 |
Coronary artery disease | 9 (17.6) | 7 (21.9) | 6 (35.3) | 0.3144 |
Chronic heart failure | 4 (7.8) | 3 (9.4) | 1 (5.9) | 0.9105 |
COPD | 15 (29.4) | 12 (37.5) | 2 (11.8) | 0.1670 |
Pulmonary function | ||||
FEV1 (% predicted) | 64.69 ± 17.88 | 67.51 ± 18.65 | 77.09 ± 20.02 | 0.0926 |
PaO2 (mmHg) | 67.62 ± 12.44 | 66.69 ± 9.01 | 69.34 ± 17.69 | 0.9264 |