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Table 3 Comparison of various index in subgroups according to severity of disease

From: The level of lipopolysaccharide-binding protein is elevated in adult patients with obstructive sleep apnea

Variables

OSA

Mild vs Moderate

Mild vs Severe

Moderate vs Severe

Mild(10)

Moderate(15)

Severe(25)

t

p value

t

p value

t

p value

Age(years)

59.60 ± 15.13

56.73 ± 15.93

52.27 ± 13.54

0.352

0.729

1.104

0.277

−0.983

0.331

BMI(kg/m2)

27.04 ± 2.58

26.81 ± 3.80

27.28 ± 3.16

0.120

0.906

−0.164

0.871

0.436

0.665

SBP(mmHg) 140.40 ± 13.05

130.31 ± 16.79

133.93 ± 16.82

1.204

0.246

0.812

0.423

0.638

0.528

 

DBP(mmHg)

85.20 ± 9.61

79.85 ± 15.63

81.04 ± 14.63

0.686

0.502

0.597

0.555

0.236

0.815

AHI

10.14 ± 2.95

22.88 ± 3.93

49.11 ± 14.96

−6.066

0.000

−12.848

0.000

−8.999

0.000

LSaO2

87.20 ± 1.30

79.53 ± 9.13

70.90 ± 12.00

3.159

0.006

6.958

0.000

2.429

0.020

mSaO2

94.80 ± 1.48

93.88 ± 2.27

92.38 ± 5.10

0.840

0.412

1.040

0.307

1.077

0.288

ODI

11.94 ± 5.37

26.41 ± 18.78

55.44 ± 22.17

−1.672

0.112

−9.008

0.000

−4.305

0.000

MAI

14.56 ± 2.87

16.45 ± 8.12

27.06 ± 17.40

−0.501

0.623

−3.484

0.002

−2.627

0.012

LBP

25.81 ± 7.16

33.55 ± 3.50

38.29 ± 7.40

−2.743

0.018

− 2.771

0.010

− 2.642

0.012

IL-1β

20.10 ± 1.47

24.35 ± 3.83

29.15 ± 5.91

−1.837

0.091

−2.604

0.015

−2.475

0.018

IL-6

46.20 ± 6.09

58.34 ± 7.09

64.76 ± 9.05

−2.686

0.020

−3.434

0.002

− 2090

0.044

TNF-α

274.64 ± 4.91

308.75 ± 42.48

341.28 ± 44.80

−2.601

0.025

−2.534

0.017

−2.048

0.048

  1. AHI Apnea-hypopnea index, BMI Body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, LSaO 2 Lowest saturation oxygen, mSaO 2 Mean saturation oxygen, ODI Oxygen desaturation index, MAI Microarousal index