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Table 3 Comparison of various index in subgroups according to severity of disease

From: The level of lipopolysaccharide-binding protein is elevated in adult patients with obstructive sleep apnea

Variables OSA Mild vs Moderate Mild vs Severe Moderate vs Severe
Mild(10) Moderate(15) Severe(25) t p value t p value t p value
Age(years) 59.60 ± 15.13 56.73 ± 15.93 52.27 ± 13.54 0.352 0.729 1.104 0.277 −0.983 0.331
BMI(kg/m2) 27.04 ± 2.58 26.81 ± 3.80 27.28 ± 3.16 0.120 0.906 −0.164 0.871 0.436 0.665
SBP(mmHg) 140.40 ± 13.05 130.31 ± 16.79 133.93 ± 16.82 1.204 0.246 0.812 0.423 0.638 0.528  
DBP(mmHg) 85.20 ± 9.61 79.85 ± 15.63 81.04 ± 14.63 0.686 0.502 0.597 0.555 0.236 0.815
AHI 10.14 ± 2.95 22.88 ± 3.93 49.11 ± 14.96 −6.066 0.000 −12.848 0.000 −8.999 0.000
LSaO2 87.20 ± 1.30 79.53 ± 9.13 70.90 ± 12.00 3.159 0.006 6.958 0.000 2.429 0.020
mSaO2 94.80 ± 1.48 93.88 ± 2.27 92.38 ± 5.10 0.840 0.412 1.040 0.307 1.077 0.288
ODI 11.94 ± 5.37 26.41 ± 18.78 55.44 ± 22.17 −1.672 0.112 −9.008 0.000 −4.305 0.000
MAI 14.56 ± 2.87 16.45 ± 8.12 27.06 ± 17.40 −0.501 0.623 −3.484 0.002 −2.627 0.012
LBP 25.81 ± 7.16 33.55 ± 3.50 38.29 ± 7.40 −2.743 0.018 − 2.771 0.010 − 2.642 0.012
IL-1β 20.10 ± 1.47 24.35 ± 3.83 29.15 ± 5.91 −1.837 0.091 −2.604 0.015 −2.475 0.018
IL-6 46.20 ± 6.09 58.34 ± 7.09 64.76 ± 9.05 −2.686 0.020 −3.434 0.002 − 2090 0.044
TNF-α 274.64 ± 4.91 308.75 ± 42.48 341.28 ± 44.80 −2.601 0.025 −2.534 0.017 −2.048 0.048
  1. AHI Apnea-hypopnea index, BMI Body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, LSaO 2 Lowest saturation oxygen, mSaO 2 Mean saturation oxygen, ODI Oxygen desaturation index, MAI Microarousal index