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Table 1 Baseline characteristics of patients with interstitial lung disease (n = 1972) and controls (n = 310,547)

From: Risk factors for interstitial lung disease: a 9-year Nationwide population-based study

Variable Interstitial lung disease No. (%) Control No. (%) P value
Sex
 Male 1265 (64.1) 151,124 (48.7) < 0.001
 Female 707 (35.9) 159,423 (51.3)  
Age group (years)
 40–49 354 (18.0) 136,576 (44.0) < 0.001
 50–59 474 (24.0) 89,952 (29.0)  
 60–69 662 (33.6) 57,189 (18.4)  
  ≥ 70 482 (24.4) 26,830 (8.6)  
Baseline comorbidity
 Malignancy 357 (18.1) 43,007 (13.8) < 0.001
 Diabetes 479 (24.3) 48,507 (15.6) < 0.001
 Chronic renal failure 27 (1.4) 2187 (0.7) < 0.001
 COPDa 242 (12.3) 11,204 (3.6) < 0.001
Past history
 Herpes (B00, B02) 65 (3.3) 9997 (3.2) 0.85
 Tuberculosis (A15, A16, B90) 102 (5.2) 5467 (1.8) < 0.001
 Pneumonia (J12-J18) 98 (5.0) 6709 (2.2) < 0.001
 Hepatitis C (B18.2) 28 (1.4) 2068 (0.7) < 0.001
 Hepatitis B (B18.0, B18.1) 66 (3.3) 9859 (3.2) 0.66
 GERDb (K21) 227 (11.5) 26,643 (8.6) < 0.001
Smoker (ex-smoker or current smoker) 748 (37.9) 93,573 (30.1) < 0.001
Household income (Quartiles), %
 81–100 870 (44.1) 131,363 (42.3) 0.11
 41–80 635 (32.2) 107,310 (34.6)  
 11–40 437 (22.2) 66,372 (21.4)  
 0–10 30 (1.5) 5502 (1.8)  
  1. aCOPD chronic obstructive pulmonary disease, b GERD gastroesophageal reflux disorder