Cross-sectional phase | Longitudinal phase | |||||
---|---|---|---|---|---|---|
Empty Spiromax followed by empty Turbuhaler (N = 243a) | Empty Turbuhaler followed by empty Spiromax (N = 242a) | P-value | BF Spiromax (N = 197a) | BF Turbuhaler (N = 197a) | P-value | |
Age, years, mean (SD) | 54.4 (13.8) | 53.1 (14.2) | 0.309b | 53.3 (14.3) | 53.1 (14.1) | 0.758b |
Height, cm, mean (SD) | 167.5 (9.1) | 169.3 (9.4) | 0.022b | 168.1 (8.9) | 168.8 (9.5) | 0.348b |
Sex, male, n (%) | 91 (37.4) | 108 (44.6) | 0.108c | 81 (41.1) | 82 (41.6) | 0.919c |
FEV1, mean (SD) | 2.5 (0.8) | 2.6 (0.8) | 0.238b | 2.5 (0.8) | 2.6 (0.9) | 0.305b |
ACQ-7, mean (SD) | 1.4 (0.9) | 1.6 (0.9) | 0.043b | 1.6 (1.0) | 1.6 (0.9) | 0.257b |
Eosinophil levels, mean cells/nL (SD) | 0.3 (0.3) | 0.3 (0.3) | 0.279b | 0.3 (0.2) | 0.3 (0.2) | 0.595b |
Medications, n (%) | ||||||
Prior medication | 199 (81.9) | 195 (80.6) | 0.711c | 179 (90.9) | 184 (93.4) | 0.350c |
Concomitant medication | 240 (98.8) | 240 (99.2) | 0.656c | 194 (98.5) | 196 (99.5) | 0.315c |