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Table 2 Sensitivity, specificity and predictive values for the detection of > 10% decrease in ∆FEV1

From: Heparin-binding protein in sputum as a marker of pulmonary inflammation, lung function, and bacterial load in children with cystic fibrosis

  Cut-off Sensitivity (%) Specificity (%) PPV (%) NPV (%)
HBP (ng/ml) 650 81 70 74 78
Elastase (U/ml) 0.15 76 70 73 74
Bacterial load (ng/ml) 0.1 47 44 50 41
  1. PPV positive predictive value, NPV negative predictive value