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Table 1 Baseline association between risk groups and the personal characteristics of the 318 subjects (median [interquartile range], % (n))

From: Do airway inflammation and airway responsiveness markers at the start of apprenticeship predict their evolution during initial training? A longitudinal study among apprentice bakers, pastry makers and hairdressers

 

NO group

Eosinophil count group

Airway responsiveness FEV1 group

Airway responsiveness resistance group

 

+a

n = 46

-a

n = 272

+b

n = 44

-b

n = 274

+c

n = 44

-c

n = 274

+d

n = 27

-d

n = 291

Sex: male 55.3% (176)

58.7% (27)

54.8% (149)

63.6% (28)

54.0% (148)

56.8% (25)

55.1% (151)

55.6% (15)

55.3% (161)

 

p = 0.62

p = 0.23

p = 0.83

p = 0.98

Atopic disposition 37.1% (118)

41.3% (19)

36.4% (99)

47.7% (21)

35.4% (97)

47.7% (21)

35.4% (97)

33.3% (9)

37.5% (109)

 

p = 0.52

p = 0.12

p = 0.12

p = 0.67

Atopic disease 18.2% (58)

15.2% (7)

18.8% (51)

6.8% (3)

20.1% (55)

15.9% (7)

18.6% (51)

22.2% (6)

17.9% (52)

 

p = 0.57

p = 0.04

p = 0.83

p = 0.60

Personal atopy based on SPT

  ≥ 1 positive response 32.1% (102)

67.4% (31)

26.1% (71)

52.3% (23)

28.8% (79)

54.6% (24)

28.5% (78)

51.9% (14)

30.2% (88)

 

p < 0.0005

p = 0.002

p = 0.001

p = 0.020

Degree of sensitization

 0 positive response

32.6% (15)

68.5% (185)

39.5% (17)

67.0% (183)

45.5% (20)

66.2% (180)

44.4% (12)

65.1% (188)

 1 to 2 positive responses

21.7% (10)

19.6% (53)

25.6% (11)

19.1% (52)

25.0% (11)

19.1% (52)

29.6% (8)

19.0% (55)

  ≥ 3 positive responses

45.7% (21)

11.9% (32)

34.9% (15)

13.9% (38)

29.6% (13)

14.7% (40)

25.9% (7)

15.9% (46)

 

p  < 0.0005

p  = 0.001

p = 0.017

p = 0.10

Training track

 Bakery- Pastry making 60.1% (191)

69.6% (32)

58.5% (159)

65.9% (29)

59.1% (162)

54.6% (24)

61.0% (167)

74.1% (20)

58.8% (171)

 Hairdressing 39.9% (127)

30.4% (14)

41.5% (113)

34.1% (15)

40.9% (112)

45.5% (20)

39.1% (107)

25.9% (7)

41.2% (120)

 

p = 0.16

p = 0.39

p = 0.42

p = 0.12

Tobacco usage status

 Non smoker 49.7% (158)

63.0% (29)

47.4% (129)

54.6% (24)

48.9% (134)

47.7% (21)

50.0% (137)

33.3% (9)

51.2% (149)

 Current smoker 46.2% (147)

32.6% (15)

48.5% (132)

43.2% (19)

46.7% (128)

50.0% (22)

45.6% (125)

63.0% (17)

44.7% (130)

 Past smoker 4.1% (13)

4.4% (2)

4.0% (11)

2.3% (1)

4.4% (12)

2.3% (1)

4.4% (12)

3.7% (1)

4.1% (12)

 

p = 0.13

p = 0.69

p = 0.74

p = 0.18

Baseline FEV1

  > 80.0% 87.1% (277)

91.3% (42)

86.4% (235)

81.8% (36)

88.0% (241)

79.6% (35)

88.3% (242)

92.6% (25)

86.6% (252)

  > 70.0 and < 80.0% 12.3% (39)

8.7% (4)

12.9% (35)

15.9% (7)

11.7% (32)

15.9% (7)

11.7% (32)

7.4% (2)

12.7% (37)

  < 70.0% 0.6% (2)

0

0.7% (2)

2.3% (1)

0.4% (1)

4.6% (2)

0

0

0.7% (2)

 

p = 0.73

p = 0.16

p = 0.012

p = 0.63

  1. aNO Group +: subjects with a baseline FeNO level > 27 ppb; −: subjects with a baseline FeNO level < 27 ppb
  2. bEosinophil Count Group +: subjects with a baseline percentage of eosinophils > 1% in the nasal lavage; −: subjects with no eosinophils at baseline
  3. cAirway Responsiveness FEV1 Group +: subjects with a baseline decrease in FEV1 of 15% or more during the MBC test; −: subjects with a baseline FEV1 decrease < 15%
  4. dAirway Responsiveness Resistance Group +: subjects with a baseline increase in resistance of 50% or more between 4 and 16 Hz; −: subjects with a baseline increase in resistance of < 50%
  5. p: p-value of the test comparing the presence or level of a marker in the +risk group and -risk group