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Fig. 4 | BMC Pulmonary Medicine

Fig. 4

From: NOX4 expression and distal arteriolar remodeling correlate with pulmonary hypertension in COPD

Fig. 4

An increased expression of NOX4, α-SMA, collage I and TGFβ1 in distal pulmonary arteries of COPD patients. a immunohistochemical (IHC) staining showed an elevated expression of NOX4, and collage I in the smooth muscle of small pulmonary artery of COPD lungs compared to normal control lungs; (b) The expression of NOX4 (top panel) and collage I (bottom panel) in non-COPD and COPD lungs determined by absorbance optical density (AOD) values of IHC. Compared to non-COPD lung, *P < 0.05, *** P < 0.01 (N = 19 for non-COPD; N = 15 for COPD). Bars = 100 μm for all images in a

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