From: NOX4 expression and distal arteriolar remodeling correlate with pulmonary hypertension in COPD
Demographics | Control | Patients with COPD | t/t’ | P | |
---|---|---|---|---|---|
Mild (GOLD1) | Moderate (GOLD2) | ||||
Subjects | 19 | 6 | 9 | Â | Â |
Age (s) | 55.84±7.82 (45–68) | 54.83±7.36 (43–64) | 54.11±6.92 (43–64) | 0.56 | 0.58 |
Gender | |||||
 Male | 13 | 6 | 6 | 0.74 | 0.46 |
 Female | 6 | 0 | 3 |  |  |
Stature (m) | 1.68±0.07 | 1.70±0.07 | 1.68±0.05 | − 0.45 | 0.65 |
Weight (kg) | 69.79±11.63 | 65.33±7.00 | 55.84±14.38 |  |  |
BSA (m2) | 1.76±0.18 | 1.72±0.12 | 1.71±0.22 | 0.86 | 0.40 |
BMI (kg/m2) | 24.69±2.95 | 22.75±2.25 | 22.77±3.56 | 1.87 | 0.07 |
Smoking status and cigarette consumption (Pack-years) | 9.66±11.83 | 19.17±14.97 | 13.33±15.81 | −1.296 | 0.20 |
Never smoking (n) | 9 | 1 | 4 | Â | Â |
Current smoking (n) | 6 | 4 | 3 | Â | Â |
Ex-smoker (n) | 4 | 1 | 2 | Â | Â |
PO2 (mmHg) | 92.51±7.34 | 60.85±8.36 | 63.63±2.72 | 7.82 | 0.00 |
PCO2 (mmHg) | 37.67±2.60 | 41.20±4.81 | 41.56±4.53 | −2.88 | 0.01 |
FEV1/FVC (%) | 76.29±6.04 | 63.67±3.56 | 53.22±8.26 | 7.30 | 0.00 |
FEV1%prep (%) | 97.74±18.80 | 91.00±4.47 | 62.22±4.09 | 4.02 | 0.00 |
DLCO(%) | 87.89 ± 8.43 | 86.00 ± 8.32 | 67.89 ± 6.49 | 3.72 | 0.00 |
6MWD (m) | 507.00±25.27 | 422.33±49.94 | 425.89±37.25 | 6.84 | 0.00 |