Table 1 Description of 1584 subjects with COPD according to GOLD 2011 Classification (frequency of each variable by COPD severity)
From: Comorbidities and COPD severity in a clinic-based cohort
A N = 435 | B N = 391 | C N = 178 | D N = 580 | p | |
|---|---|---|---|---|---|
Males, % | 68.5 | 62.6 | 62.9 | 64.6 | 0.3006 |
Age, yr (SD) | 63.2(10.4) | 69(10.8) | 63.6(10.6) | 68.2(11) | 0.0006 |
BMI, (kg/m2), % < 21 | 0.0001 | ||||
(underweight) [21–26[(normal) | 12.4 | 13.3 | 21.3 | 19.6 | |
[26–29[(overweight) | 37.7 | 30.2 | 33.2 | 36.4 | |
> 29 (obese) | 21.8 | 21.2 | 22.5 | 17.6 | |
28.3 | 35.3 | 23 | 26.4 | ||
FEV1, % pred | 0.0001 | ||||
> 80% | 109(25) | 55(14) | 26(14.6) | 13(2.2) | |
50–80% | 326(75) | 336(86) | 62(34.9) | 141(24.3) | |
30–50% | – | – | 85(47.8) | 328(56.5) | |
< 30% | – | – | 5(2.8) | 98(16.9) | |
mMRC 0–1, n(%) | 435(100) | 0 | 178(100) | 0 | 0.0001 |
mMRC > =2, n(%) | 0 | 391(100) | 0 | 580(100) | 0.0001 |
Chronic cough, n(%) | 190(43.6) | 222(56.7) | 96(53.9) | 402(69.3) | < 0.0001 |
Current smokers, n(%) | 170(39.8) | 131(34.5) | 68(39.5) | 195(34.5) | 0.2394 |
0–1 exacerbation previous year, n(%) | 435(100) | 391(100) | 71(40) | 231(39.8) | 0.0001 |
> = 2 exacerbations, previous year, n(%) | 0 | 0 | 107(60) | 349(60.2) | 0.0001 |
Pulmonary rehabilitation, n(%) | 12(2.7) | 23(5.8) | 10(5.6) | 97(16.7) | < 0.0001 |
Smoking cessation, n(%) | 35(8.0) | 23(5.8) | 26(14.6) | 58(10) | 0.0053 |
SABA, % | 28.7 | 44.2 | 37 | 47 | < 0.0001 |
LABA, or LAMA, % | 53.1 | 72.1 | 66.8 | 71.2 | < 0.0001 |
ICS and LABA, % | 18.1 | 24.8 | 24.2 | 39 | < 0.0001 |
Annual influenza vaccination, n(%) | 166(38.1) | 230(58.8) | 93(52.2) | 410(70.6) | < 0.0001 |
Pneumococcal vaccination, n(%) | 141(32.4) | 204(52.1) | 100(56.1) | 379(65.3) | < 0.0001 |