Table 1 Clinical characteristics in patients with severe COPD in relation to the relative lymphocyte count at baseline
From: Relative lymphocyte count as an indicator of 3-year mortality in elderly people with severe COPD
Variablea | Relative lymphocyte count ≤20% (N = 85) | Relative lymphocyte count > 20% (N = 133) | p-value |
|---|---|---|---|
Sex (M/F) | 46/39 | 68/65 | 0.67 |
Age (years) | 76±7 | 74±7 | 0.06 |
Bodymass index (BMI) | 25.7±5 | 25.4±4 | 0.66 |
History of smoking (n/%) | 43 (51%) | 72 (54%) | 0.61 |
Alcohol use (n/%) | 30 (35%) | 48 (36%) | 0.90 |
Lung Function | |||
 FEV1 (ml) | 762±268 | 870±268 | 0.004 |
 FEV1 (percent of predicted) | 30±9 | 34±8 | 0.005 |
 FVC (ml) | 1720±656 | 2038±687 | 0.001 |
 FVC (percent of predicted) | 53±17 | 62±17 | < 0.0001 |
 FEV1/FVC (percent) | 47±13 | 44±11 | 0.16 |
Arterial Blood Gases | |||
 PaO2 (mmHg) | 71±9 | 70±8 | 0.79 |
 PaCO2 (mmHg) | 38±5 | 37±4 | 0.12 |
 pH | 7.40±0.39 | 7.40±0.41 | 0.47 |
Disease (n/%) | |||
 Ischemic heart disease | 21 (25%) | 49 (37%) | 0.027 |
 History of myocardial infarction | 20 (24%) | 54 (41%) | 0.0091 |
 Congestive heart failure | 32 (38%) | 15 (11%) | 0.0001 |
 Corpulmonale | 43 (51%) | 49 (37%) | 0.031 |
 Diabetes | 19 (22%) | 25 (19%) | 0.52 |
 Systemic hypertension | 40 (47%) | 65 (49%) | 0.79 |
 Cerebro-vascular disease | 20 (24%) | 32 (24%) | 0.93 |
 Peripheral vascular disease | 11 (13%) | 17 (13%) | 0.97 |
Therapy (n/%) | |||
 Bronchodilators | 66 (78%) | 100 (75%) | 0.68 |
 Mucolytics | 70 (82%) | 101 (76%) | 0.26 |
 Aminophylline | 53 (62%) | 112 (69%) | 0.029 |
Heart rate (bpm) | 95±22 | 82±19 | < 0.0001 |
Systolic blood pressure (mmHg) | 139±25 | 142±20 | 0.42 |
Diastolic blood pressure (mmHg) | 78±11 | 81±9 | 0.031 |