Table 1 Study population characteristics, 5907 parents and 6752 offspring included in the RHINESSA generation study
From: Agreement in reporting of asthma by parents or offspring – the RHINESSA generation study
Characteristics | Parents (RHINE/ECRHS) | Children (RHINESSA) | ||||
|---|---|---|---|---|---|---|
Mother | Father | Pa | Daughter | Son | Pa | |
N (%) | N (%) | N (%) | N (%) | |||
N (%) | 3377 (57) | 2530 (43) | 3910 (58) | 2842 (42) | ||
Albacete | 39 (57) | 30 (43) | 39 (53) | 34 (47) | ||
Bergen | 593 (53) | 518 (47) | 706 (60) | 480 (40) | ||
Gothenburg | 413 (56) | 322 (44) | 491 (53) | 439 (47) | ||
Huelva | 42 (69) | 19 (31) | 44 (64) | 25 (36) | ||
Melbourne | 96 (55) | 80 (45) | 42 (62) | 26 (38) | ||
Reykjavik | 409 (55) | 328 (45) | 543 (61) | 342 (39) | ||
Tartu | 205 (68) | 97 (32) | 177 (60) | 119 (40) | ||
Umea | 629 (60) | 423 (40) | 735 (57) | 545 (43) | ||
Uppsala | 602 (59) | 420 (41) | 713 (56) | 556 (44) | ||
Aarhus | 349 (54) | 293 (46) | 420 (60) | 276 (40) | ||
Mean age (SD) | 54.0 (6.5) | 54.7 (6.1) | < 0.001 | 30.3 (7.7) | 30.4 (7.8) | 0.930 |
Asthma (%) | 478 (14) | 292 (12) | 0.004 | 671 (17) | 420 (15) | 0.008 |
Smoking | 0.009 | < 0.001 | ||||
Never-smokers | 1496 (46) | 1155 (47) | 2602 (67) | 1942 (69) | ||
Ex-smokers | 1400 (43) | 1100 (45) | 850 (22) | 503 (18) | ||
Current smokers | 337 (10) | 197 (8) | 445 (11) | 382 (14) | ||
Education | < 0.001 | < 0.001 | ||||
Primary school | 385 (12) | 296 (12) | 97 (3) | 91 (3) | ||
Secondary school | 1224 (38) | 1029 (44) | 1282 (33) | 1259 (44) | ||
College/university | 1576 (50) | 1068 (45) | 2521 (65) | 1487 (52) | ||
Parental asthma | 0.058 | < 0.001 | ||||
Mother | 295 (10) | 206 (9) | 476 (12) | 272 (10) | ||
Father | 218 (7) | 124 (6) | 309 (8) | 179 (6) | ||
No one | 2518 (83) | 1922 (85) | 3038 (79) | 2333 (83) | ||
Both | 12 (0.4) | 12 (0.5) | 39 (2) | 23 (1) | ||
Other diseasesb | ||||||
Comorbidity | 892 (26) | 778 (31) | < 0.001 | 165 (4) | 124 (4) | 0.770 |
Hypertension | 778 (23) | 659 (26) | 0.005 | 120 (3) | 96 (4) | 0.390 |
Stroke | 54 (2) | 46 (2) | 0.510 | – | – | – |
Ischemic heart disease | 64 (2) | 116 (5) | < 0.001 | 5 (0.1) | 8 (0.3) | 0.150 |
Diabetes mellitus | 106 (3) | 107 (5) | 0.027 | 53 (1) | 30 (1) | 0.270 |
COPD | 73 (2) | 60 (2) | 0.600 | 10 (0.3) | 5 (0.2) | 0.490 |
Serious childhood infection < 5 years | 254 (8) | 126 (5) | < 0.001 | 331 (9) | 185 (7) | < 0.001 |
Respiratory symptoms | 0.246 | 0.001 | ||||
Wheezec | 669 (20) | 530 (21) | 0.330 | 697 (18) | 468 (17) | 0.150 |
Wheeze with shortness of breathc | 421 (13) | 297 (12) | 0.380 | 457 (62) | 256 (49) | < 0.001 |
Awoken with tightness in chestc | 364 (11) | 245 (10) | 0.170 | 497 (13) | 286 (10) | < 0.001 |
Awoken with attack of breathlessnessc | 220 (7) | 126 (5) | 0.013 | 173 (4) | 136 (5) | 0.48 |
Awoken with attack of coughc | 1093 (33) | 533 (21) | < 0.001 | 1343 (34 | 562 (20) | < 0.001 |
Currently taking asthma medication | 327 (10) | 216 (9) | 0.130 | 383 (10) | 212 (8) | < 0.001 |