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Table 2 Parameter estimates (95% CI) for Cohen’s kappa, sensitivity, specificity, PPV and NPV for offspring-reported parental asthma and parent-reported offspring asthma

From: Agreement in reporting of asthma by parents or offspring – the RHINESSA generation study

Offspring asthma Agreementa N (%) Disagreementb N (%) Cohens kappa Sensitivity 95% CI Specificity 95% CI PPV 95% CI NPV 95% CI
 Early onset asthma 5121 (96) 219 (4) 0.72 0.68 0.64, 0.72 0.99 0.98, 0.99 0.83 0.79, 0.86 0.97 0.96, 0.97
  Mother 2935 (96) 110 (4) 0.75 0.72 0.66, 0.77 0.99 0.98, 0.99 0.83 0.77, 0.88 0.98 0.97, 0.98
  Father 2186 (95) 109 (5) 0.69 0.64 0.57, 0.70 0.99 0.98, 0.99 0.83 0.76, 0.88 0.96 0.95, 0.97
 Late onset asthma 5001 (93) 376 (7) 0.46 0.36 0.32, 0.41 0.99 0.98, 0.99 0.79 0.73, 0.84 0.94 0.93, 0.94
  Mother 2891 (94) 199 (6) 0.53 0.43 0.37, 0.49 0.99 0.98, 0.99 0.82 0.75, 0.88 0.94 0.93, 0.95
  Father 2110 (92) 177 (8) 0.36 0.26 0.21, 0.33 0.99 0.98, 0.99 0.73 0.61, 0.82 0.93 0.92, 0.94
Parental asthma
 Maternal 3477 (93) 276 (7) 0.69 0.72 0.68, 0.75 0.96 0.95, 0.97 0.75 0.71, 0.79 0.95 0.95, 0–96
  Daughter 2009 (92) 163 (8) 0.69 0.75 0.69, 0.79 0.95 0.94, 0.96 0.71 0.66, 0.76 0.96 0.95, 0.97
  Son 1468 (93) 113 (7) 0.70 0.68 0.61, 0.74 0.97 0.96, 0.98 0.81 0.75, 0.86 0.95 0.93, 0.96
 Paternal 2817 (94) 182 (6) 0.68 0.68 0.63, 0.73 0.97 0.96, 0.98 0.76 0.71, 0.80 0.96 0.95, 0.97
  Daughter 1637 (94) 101 (6) 0.71 0.72 0.65, 0.78 0.97 0.96, 0.98 0.77 0.70, 0.83 0.96 0.95, 0.97
  Son 1180 (94) 81 (6) 0.64 0.63 0.54, 0.71 0.97 0.96, 0.98 0.74 0.65, 0.82 0.96 0.94, 0.97
  1. aAgreement: when both parents and offspring answered the same (yes/yes or no/no)
  2. bDisagreement: when parents and offspring answered differently (yes/no or no/yes)