Agreement in reporting of asthma by parents or offspring – the RHINESSA generation study

BMC Pulmonary Medicine

Table 2 Parameter estimates (95% CI) for Cohen’s kappa, sensitivity, specificity, PPV and NPV for offspring-reported parental asthma and parent-reported offspring asthma

Offspring asthma	Agreement^a N (%)	Disagreement^b N (%)	Cohens kappa	Sensitivity	95% CI	Specificity	95% CI	PPV	95% CI	NPV	95% CI
Early onset asthma	5121 (96)	219 (4)	0.72	0.68	0.64, 0.72	0.99	0.98, 0.99	0.83	0.79, 0.86	0.97	0.96, 0.97
Mother	2935 (96)	110 (4)	0.75	0.72	0.66, 0.77	0.99	0.98, 0.99	0.83	0.77, 0.88	0.98	0.97, 0.98
Father	2186 (95)	109 (5)	0.69	0.64	0.57, 0.70	0.99	0.98, 0.99	0.83	0.76, 0.88	0.96	0.95, 0.97
Late onset asthma	5001 (93)	376 (7)	0.46	0.36	0.32, 0.41	0.99	0.98, 0.99	0.79	0.73, 0.84	0.94	0.93, 0.94
Mother	2891 (94)	199 (6)	0.53	0.43	0.37, 0.49	0.99	0.98, 0.99	0.82	0.75, 0.88	0.94	0.93, 0.95
Father	2110 (92)	177 (8)	0.36	0.26	0.21, 0.33	0.99	0.98, 0.99	0.73	0.61, 0.82	0.93	0.92, 0.94
Parental asthma
Maternal	3477 (93)	276 (7)	0.69	0.72	0.68, 0.75	0.96	0.95, 0.97	0.75	0.71, 0.79	0.95	0.95, 0–96
Daughter	2009 (92)	163 (8)	0.69	0.75	0.69, 0.79	0.95	0.94, 0.96	0.71	0.66, 0.76	0.96	0.95, 0.97
Son	1468 (93)	113 (7)	0.70	0.68	0.61, 0.74	0.97	0.96, 0.98	0.81	0.75, 0.86	0.95	0.93, 0.96
Paternal	2817 (94)	182 (6)	0.68	0.68	0.63, 0.73	0.97	0.96, 0.98	0.76	0.71, 0.80	0.96	0.95, 0.97
Daughter	1637 (94)	101 (6)	0.71	0.72	0.65, 0.78	0.97	0.96, 0.98	0.77	0.70, 0.83	0.96	0.95, 0.97
Son	1180 (94)	81 (6)	0.64	0.63	0.54, 0.71	0.97	0.96, 0.98	0.74	0.65, 0.82	0.96	0.94, 0.97

^aAgreement: when both parents and offspring answered the same (yes/yes or no/no)
^bDisagreement: when parents and offspring answered differently (yes/no or no/yes)

ISSN: 1471-2466