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Table 3 Odds ratios for discrepant answers in offspring/parent asthma reports, univariate and multivariate logistic regression analysis

From: Agreement in reporting of asthma by parents or offspring – the RHINESSA generation study

Predictor

Univariate analyses Parents

Multivariate analysesa Parents

Univariate analyses Offspring

Multivariate analysesa Offspring

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

Male gender

1.33 (1.11, 1.60)

0.002

1.31 (1.08, 1.59)

0.007

1.01 (0.84, 1.23)

0.905

  

Age

1.00 (0.99, 1.02)

0.630

  

1.01 (1.00, 1.02)

0.058

  

Smoking

 Never smoker

1.00

 

1.00

 

1.00

   

 Current smoker

1.51 (1.11, 2.05)

0.009

1.46 (1.05, 2.02)

0.023

1.14 (0.85, 1.52)

0.392

  

 Ex-smoker

1.28 (1.05, 1.56)

0.013

1.22 (0.99, 1.50)

0.062

1.31 (1.04, 1.64)

0.021

1.22 (0.95, 1.55)

0.114

Education

 College/university

1.00

   

1.00

   

 Primary school

1.25 (0.94, 1.66)

0.127

  

1.59 (0.97, 2.59)

0.065

  

 Secondary school

1.04 (0.86, 1.28)

0.641

  

1.03 (0.85, 1.26)

0.756

  

Comorbidity

 Hypertension

0.93 (0.75, 1.15)

0.505

  

1.42 (0.89, 2.28)

0.140

  

 Stroke

1.03 (0.52, 2.06)

0.930

  

  

 Ischemic heart

1.88 (1.23, 2.86)

0.003

1.54 (0.96, 2.46)

0.071

  

 Diabetes

1.64 (1.09, 2.46)

0.018

1.46 (0.96, 2.24)

0.077

1.07 (0.47, 2.48)

0.868

  

 COPD

1.75 (1.07, 2.87)

0.026

1.49 (0.89, 2.50)

0.129

  

 Serious childhood infection < 5 years

1.12 (0.99, 1.27)

0.080

  

1.11 (0.98, 1.25)

0.106

  

Respiratory symptoms

 Wheeze

1.32 (1.07, 1.63)

0.010

1.02 (0.72, 1.46)

0.902

1.58 (1.26, 1.97)

< 0.001

1.60 (1.21, 2.11)

0.001

 Wheeze with shortness of breath

1.47 (1.15, 1.89)

0.002

1.22 (0.81, 1.84)

0.343

1.37 (0.92, 2.04)

0.127

  

 Awoken with tightness in chest

1.01 (0.76, 1.36)

0.924

  

1.16 (0.87, 1.53)

0.313

  

 Awoken with attack of breathlessness

1.26 (0.89, 1.80)

0.193

  

1.11 (0.72, 1.72)

0.634

  

 Awoken with attack of cough

1.28 (1.05, 1.55)

0.013

1.25 (1.00, 1.57)

0.046

0.94 (0.76, 1.16)

0.557

  

 Currently taking asthma medication

1.32 (1.00, 1.76)

0.058

  

1.42 (1.06, 1.91)

0.020

0.95 (0.60, 1.49)

0.823

Age of onset

 Early onset

  

1.12 (0.78, 1.62)

0.528

  

 Late onset

  

1.76 (1.32, 2.34)

< 0.001

1.45 (1.01, 2.07)

0.042

  1. aAdjusted for all predictors that were significant in the univariate analyses as well as for study centre and sibling status