Table 2 Comparison of the change and changing rate of patients’ variables between the baseline and the endpoint among four groups
From: The influence of anemia on one-year exacerbation rate of patients with COPD-PH
Variables | COPD-PH-anemia (n = 40) | COPD-PH (n = 42) | COPD-anemia (n = 48) | COPD (n = 50) | P value |
|---|---|---|---|---|---|
FEV1-% (%) | −8.8 ± 3.6(− 10.1 ± 5.3) | −8.5 ± 6.4(− 10.6 ± 4.6) | − 7.2 ± 5.1(− 8.3 ± 7.2) | −7.6 ± 4.2(−9.1 ± 4.8) | 0.057(0.062) |
CAT score-points (%) | 12.6 ± 5.8(23.7 ± 15.1) | 6.5 ± 3.7(19.2 ± 12.4) | 6.6 ± 4.0(22.3 ± 10.6) | 4.7 ± 3.2(20.1 ± 8.8) | 0.001(0.002) |
6MWD-m (%) | −59.5 ± 45.6(− 32.2 ± 18.8) | −34.3 ± 41.2(− 26.5 ± 14.3) | −28.4 ± 40.1(− 20.5 ± 16.2) | − 19.7 ± 38.3(− 16.5 ± 12.3) | 0.007(0.01) |
NT-pro BNP- ng/L (%) | 597.1 ± 154.4(31.3 ± 20.4) | 466.8 ± 191.0(25.5 ± 22.3) | 125.7 ± 112.1(19.5 ± 17.2) | 133.6 ± 108.5(15.2 ± 13.3) | <0.001(0.03) |
PaO2-mmHg (%) | −10.7 ± 5.8(− 10.9 ± 8.6) | −7.6 ± 5.3(− 11.7 ± 7.0) | −6.6 ± 5.4(−8.8 ± 7.5) | − 4.9 ± 4.5(− 7.9 ± 7.2) | 0.03(0.086) |
Peak VO2-ml/min/kg (%) | −3.5 ± 1.6(− 32.4 ± 10.3) | −2.8 ± 1.9(− 25.5 ± 13.6) | −2.4 ± 2.1(− 17.7 ± 8.8) | −1.8 ± 1.4(− 10.3 ± 11.7) | 0.021(0.009) |